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IHC (Immunohistochemistry)
(Osteocalcin Antibody-Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human Osteocalcin Polyclonal Antibody | anti-BGLAP antibody
Osteocalcin Rabbit anti-Human Polyclonal Antibody
Gene Names
BGLAP; OC; BGP; OCN
Reactivity
Human
Applications
Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
Osteocalcin, Antibody; Osteocalcin Rabbit anti-Human Polyclonal Antibody; PathPlus Osteocalcin Antibody; BGLAP; Bone Gla protein; BGP; OC; Osteocalcin; anti-BGLAP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.1% Sodium Azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-BGLAP antibody
IHC (Immunohistochemistry)
Target
Human Osteocalcin
Immunogen
LP-11003, synthetic peptide
Conjugation
Unconjugated
Preparation and Storage
Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.
IHC (Immunohistochemistry)
(Osteocalcin Antibody-Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(Osteocalcin Antibody-Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(Osteocalcin Antibody-Human Osteoblastoma: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(Osteocalcin Antibody-Human Osteoblastoma: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(Osteocalcin Antibody-Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(Osteocalcin Antibody-Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(Osteocalcin Antibody-Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(Osteocalcin Antibody-Human Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-BGLAP antibody
Osteocalcin antibody is an unconjugated rabbit polyclonal antibody to Osteocalcin from human. Validated for IHC.
BGLAP (Osteocalcin) is a protein secreted by osteoblasts that functions in metabolic regulation. It is pro-osteoblastic (bone-building) and is involved in bone mineralization and calcium ion homeostasis. Osteocalcin functions as a hormone that induces beta cells in the pancreas to release more insulin. It also directs fat cells to release adiponectin, thus increasing sensitivity to insulin. It enhances testosterone synthesis and is involved in male fertility. It is thought to promote growth and invasion in pancreatic cancer cells, and additionally some genetic BGLAP variants are associated with increased risk for hepatitis B virus-related hepatocellular carcinoma. In immunohistochemistry, BGLAP has secretory and extracellular positivity in the myometrium, brain, gastrointestinal tract, liver, pancreas, muscle and at low to variable levels in other tissues throughout the body.
BGLAP (Osteocalcin) is a protein secreted by osteoblasts that functions in metabolic regulation. It is pro-osteoblastic (bone-building) and is involved in bone mineralization and calcium ion homeostasis. Osteocalcin functions as a hormone that induces beta cells in the pancreas to release more insulin. It also directs fat cells to release adiponectin, thus increasing sensitivity to insulin. It enhances testosterone synthesis and is involved in male fertility. It is thought to promote growth and invasion in pancreatic cancer cells, and additionally some genetic BGLAP variants are associated with increased risk for hepatitis B virus-related hepatocellular carcinoma. In immunohistochemistry, BGLAP has secretory and extracellular positivity in the myometrium, brain, gastrointestinal tract, liver, pancreas, muscle and at low to variable levels in other tissues throughout the body.
References
The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Mol Cancer. 2007 Dec 28;6:83, PMID: 18163903; PLoS One. 2015 Jan 14;10(1):e0116479, PMID: 25587715
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,963 Da
NCBI Official Full Name
osteocalcin preproprotein
NCBI Official Synonym Full Names
bone gamma-carboxyglutamate (gla) protein
NCBI Official Symbol
BGLAP
NCBI Official Synonym Symbols
OC; BGP; OCN
NCBI Protein Information
osteocalcin; bone Gla protein; gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin)
UniProt Protein Name
Osteocalcin
UniProt Gene Name
BGLAP
UniProt Synonym Gene Names
BGP
UniProt Entry Name
OSTCN_HUMAN
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Product Notes
The BGLAP bglap (Catalog #AAA163021) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Osteocalcin Rabbit anti-Human Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Osteocalcin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the BGLAP bglap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Osteocalcin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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