IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46637(OTUD7B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Rabbit anti-Human, Mouse OTUD7B Polyclonal Antibody | anti-OTUD7B antibody
OTUD7B Antibody
Gene Names
OTUD7B; ZA20D1; CEZANNE
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
OTUD7B, Antibody; OTUD7B Antibody; ZA20D1; CEZANNE; anti-OTUD7B antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total OTUD7B protein.
Purity/Purification
Antigen affinity purification
Form/Format
In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1.3mg/ml (varies by lot)
Sequence Length
843
Applicable Applications for anti-OTUD7B antibody
IHC (Immunohistochemistry)
Immunogen
Synthetic peptide corresponding to internal residues of human OTUD7B
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.
IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46637(OTUD7B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
IHC (Immunohiostchemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 46637(OTUD7B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
IHC (Immunohistochemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46637(OTUD7B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
IHC (Immunohistochemistry)
(The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 46637(OTUD7B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200))
Related Product Information for anti-OTUD7B antibody
OTUD7B (OTU domain-containing protein 7B), also known as ZA20D1 or Cezanne, is an 843 amino acid protein that localizes to both the nucleus and the cytoplasm. Expressed in a variety of tissues, including liver, kidney, heart and immature B-cells, OTUD7B functions to hydrolyze branched and linear forms of polyubiquitin, specifically deubiquinating Lys-48- and Lys-63-linked polyubiquitin chains. Via its ability to deubiquinate target proteins, OTUD7B regulates the inflammatory response within the cell and may play a role in cell survival. More specifically, OTUD7B forms a negative feedback loop in pro-inflammatory signaling, thereby suppressing NF?B activity and helping to resolve inflammatory responses. OTUD7B contains one C-terminal A20-type zinc finger, one OTU domain and one N-terminal TRAF-binding domain through which it conveys its deubiquitinating activity.
Product Categories/Family for anti-OTUD7B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
88,947 Da
NCBI Official Full Name
OTU domain-containing protein 7B
NCBI Official Synonym Full Names
OTU deubiquitinase 7B
NCBI Official Symbol
OTUD7B
NCBI Official Synonym Symbols
ZA20D1; CEZANNE
NCBI Protein Information
OTU domain-containing protein 7B
UniProt Protein Name
OTU domain-containing protein 7B
UniProt Gene Name
OTUD7B
UniProt Synonym Gene Names
ZA20D1; Cezanne
Similar Products
Product Notes
The OTUD7B otud7b (Catalog #AAA310444) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OTUD7B Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's OTUD7B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the OTUD7B otud7b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OTUD7B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.