Rabbit P2RY12 / P2Y12 Polyclonal Antibody | anti-P2RY12 antibody

Rabbit Polyclonal to Human P2RY12 / P2Y12

Cat. Num. AAA51260

• Gene Names: P2RY12; HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
• Reactivity: Gorilla, Human; Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
• Applications: Immunocytochemistry, Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: P2RY12 / P2Y12, Antibody; Rabbit Polyclonal to Human P2RY12 / P2Y12; Anti-P2RY12 / P2Y12 Antibody (N-Terminus) IHC-plus; P2RY12; ADP-glucose receptor; ADPG-R; p2Y(12)R; p2Y(ADP); p2T(AC); p2Y12; Platelet ADP receptor; SP1999; p2RY12; p2Y purinoceptor 12; Purinergic receptor P2RY12; BDPLT8; Gi-coupled ADP receptor HORK3; HORK3; p2Y(AC); p2Y(cyc); p2Y12 platelet ADP receptor; Human P2RY12; P2Y12; anti-P2RY12 antibody

• Host: Rabbit
• Reactivity: Gorilla, Human; Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human P2RY12 / P2Y12. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 342

• Applicable Applications for anti-P2RY12 antibody: ICC (Immunocytochemistry), IHC (Immunohistochemistry)
• Target Species: Human
• Immunogen Description: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human P2RY12 / P2Y12. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%); Gibbon, Marmoset (88%); Pig (82%).
• Immunogen Type: Synthetic peptide
• Immunogen: P2RY12 / P2Y12 antibody was raised against synthetic 17 amino acid peptide from N-terminal extracellular domain of human P2RY12 / P2Y12. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%); Gibbon, Marmoset (88%); Pig (82%).
• Antigen Modification: N-Terminus
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Transfection Control

(Anti-P2RY12 / P2Y12 antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with P2RY12 / P2Y12.)

IHC (Immunohiostchemistry)

(Anti-P2RY12 / P2Y12 antibody IHC of human blood, platelets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

IHC (Immunohistochemistry)

(Anti-P2RY12 / P2Y12 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-P2RY12 antibody

P2Y12 is a Purinergic Receptor essential for the aggregation of blood platelets. There is evidence that mutations in P2Y12 cause a bleeding disorder, suggesting that knowledge of the P2Y12 receptor could advance the development of antiplatelet agents to treat cardiovascular diseases.

Product Categories/Family for anti-P2RY12 antibody

Family: GPCR; Subfamily: Purinergic

NCBI and Uniprot Product Information

• NCBI GI #: 12232483
• NCBI GeneID: 64805
• NCBI Accession #: NP_073625.1
• NCBI GenBank Nucleotide #: NM_022788.4
• UniProt Accession #: Q9H244; Q546J7; D3DNJ5
• Molecular Weight: 39,439 Da
• NCBI Official Full Name: P2Y purinoceptor 12
• NCBI Official Synonym Full Names: purinergic receptor P2Y, G-protein coupled, 12
• NCBI Official Symbol: P2RY12
• NCBI Official Synonym Symbols: HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)
• NCBI Protein Information: P2Y purinoceptor 12; ADP-glucose receptor; purinergic receptor P2RY12; P2Y12 platelet ADP receptor; Gi-coupled ADP receptor HORK3; G-protein coupled receptor SP1999; putative G-protein coupled receptor
• UniProt Protein Name: P2Y purinoceptor 12
• UniProt Gene Name: P2RY12
• UniProt Synonym Gene Names: HORK3; P2Y12; ADPG-R; P2Y(ADP)
• UniProt Entry Name: P2Y12_HUMAN