IHC (Immunohiostchemistry)
(Immunohistochemistry of p53R2 in human lung tissue with p53R2 antibody at 1 ug/mL.)
Rabbit p53R2 Polyclonal Antibody | anti-p53R2 antibody
p53R2 Antibody
Gene Names
RRM2B; P53R2; MTDPS8A; MTDPS8B
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
p53R2, Antibody; p53R2 Antibody; anti-p53R2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
351
Applicable Applications for anti-p53R2 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a synthetic peptide corresponding to amino acids 2 to 17 of human p53R2.
Target Name
p53R2
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of p53R2 in human lung tissue with p53R2 antibody at 1 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of p53R2 in human lung tissue with p53R2 antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of p53R2 expression in A431 cell lysate at (A) 0.5 and (B) 1 ug /ml.)
WB (Western Blot)
(Western blot analysis of p53R2 expression in A431 cell lysate at (A) 0.5 and (B) 1 ug /ml.)
Related Product Information for anti-p53R2 antibody
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and gamma-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression.
Product Categories/Family for anti-p53R2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
48,787 Da
NCBI Official Full Name
ribonucleotide reductase
NCBI Official Synonym Full Names
ribonucleotide reductase M2 B (TP53 inducible)
NCBI Official Symbol
RRM2B
NCBI Official Synonym Symbols
P53R2; MTDPS8A; MTDPS8B
NCBI Protein Information
ribonucleoside-diphosphate reductase subunit M2 B
UniProt Protein Name
Ribonucleoside-diphosphate reductase subunit M2 B
UniProt Gene Name
RRM2B
UniProt Synonym Gene Names
P53R2; p53R2
UniProt Entry Name
RIR2B_HUMAN
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Product Notes
The p53R2 rrm2b (Catalog #AAA304780) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The p53R2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's p53R2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the p53R2 rrm2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p53R2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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