WB (Western Blot)
(Western blot analysis of PAK1IP1 expression in PAK1 interacting protein 1 transfected 293T cell lysate, The lane on the left is treated with the antigen-specific peptide.)
Rabbit anti-Human, Mouse PAK1IP1 Polyclonal Antibody | anti-PAK1IP1 antibody
PAK1IP1 Antibody
Gene Names
PAK1IP1; PIP1; MAK11; WDR84; hPIP1; bA421M1.5
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PAK1IP1, Antibody; PAK1IP1 Antibody; bA421M1.5; FLJ20624; hPIP 1; hPIP1; MAK 11; MAK11; p21 activated protein kinase interacting protein 1; PAK-AND PLC-INTERACTING PROTEIN 1; PAK/PLC interacting protein 1; PAK1 interacting protein; PAK1IP1; PIP 1; PIP1; Putative PAK inhibitor Skb15; RP11 421M1.5; WD repeat containing protein 84; WDR 84; WDR84; anti-PAK1IP1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
PAK1IP1 antibody detects endogenous levels of total PAK1IP1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
392
Applicable Applications for anti-PAK1IP1 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthesized peptide
Subcellular Location
Nuclear, Nucleolus.
Tissue Specificity
Expressed in brain, colon, heart, kidney, liver, lung, muscle, peripheral blood leukocytes, placenta, small intestine, spleen and thymus.
Conjugation
Unconjugated
WB (Western Blot)
(Western blot analysis of PAK1IP1 expression in PAK1 interacting protein 1 transfected 293T cell lysate, The lane on the left is treated with the antigen-specific peptide.)
WB (Western Blot)
(Western blot analysis of PAK1IP1 expression in PAK1 interacting protein 1 transfected 293T cell lysate, The lane on the left is treated with the antigen-specific peptide.)
IHC (Immunohistochemistry)
(AAA323488 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
IHC (Immunohistochemistry)
(AAA323488 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)
Related Product Information for anti-PAK1IP1 antibody
Function: Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42. May be involved in ribosomal large subunit assembly (PubMed:24120868).
Subunit Structure: Interacts with PAK1.
Subunit Structure: Interacts with PAK1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 48 kDa
Predicted: 44 kDa
Predicted: 44 kDa
NCBI Official Full Name
p21-activated protein kinase-interacting protein 1
NCBI Official Synonym Full Names
PAK1 interacting protein 1
NCBI Official Symbol
PAK1IP1
NCBI Official Synonym Symbols
PIP1; MAK11; WDR84; hPIP1; bA421M1.5
NCBI Protein Information
p21-activated protein kinase-interacting protein 1
UniProt Protein Name
p21-activated protein kinase-interacting protein 1
UniProt Gene Name
PAK1IP1
UniProt Synonym Gene Names
PIP1; WDR84; hPIP1
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Product Notes
The PAK1IP1 pak1ip1 (Catalog #AAA323488) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAK1IP1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PAK1IP1 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PAK1IP1 pak1ip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAK1IP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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