ICC (Immunocytochemistry)
(Immunocytochemistry of Parc in Daudi cells with Parc antibody at 1 ug/mL.)
Rabbit anti-Human, Mouse PARC Polyclonal Antibody | anti-PARC antibody
PARC Antibody
Gene Names
CUL9; PARC; H7AP1
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
PARC, Antibody; PARC Antibody; p53-associated parkin-like cytoplasmic protein, UbcH7-associated protein 1; anti-PARC antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
2517
Applicable Applications for anti-PARC antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide from near the carboxy terminus of human PARC.
Target Name
PARC
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of Parc in Daudi cells with Parc antibody at 1 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of Parc in Daudi cells with Parc antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of PARC in Daudi lysate with PARC antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of PARC in Daudi lysate with PARC antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-PARC antibody
The continued localization of p53 to the nucleus is essential for its function as a tumor suppressor. PARC, a large, Parkin-like ubiquitin ligase has recently been identified as a cytoplasmic anchor protein in p53-associated protein complexes. In the absence of stress, PARC inactivation results in nuclear localization of p53 and activation of p53-dependent apoptosis, while overexpression of this protein promoted cytoplasmic sequestration of p53. Surprisingly, PARC knockout mice were viable and exhibited no obvious phenotype, suggesting that other proteins, such as the highly related cullin family of E3 ubiquitin ligases, may perform similar functions in the absence of PARC. Additionally, it has been suggested that p53 binding to PARC may serve to control PARC function.
Product Categories/Family for anti-PARC antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
268,362 Da
NCBI Official Full Name
cullin-9
NCBI Official Synonym Full Names
cullin 9
NCBI Official Symbol
CUL9
NCBI Official Synonym Symbols
PARC; H7AP1
NCBI Protein Information
cullin-9
UniProt Protein Name
Cullin-9
UniProt Gene Name
CUL9
UniProt Synonym Gene Names
H7AP1; KIAA0708; PARC; CUL-9
UniProt Entry Name
CUL9_HUMAN
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Product Notes
The PARC cul9 (Catalog #AAA305465) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PARC Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PARC can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PARC cul9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PARC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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