WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells (Lane 2) and HepG2 cells (Lane 3), using Patched antiobdy. The lane on the left is treated with synthesized peptide.)
Rabbit anti-Human, Mouse Patched Polyclonal Antibody | anti-Patched antibody
Patched Antibody
Gene Names
PTCH1; PTC; BCNS; HPE7; PTC1; PTCH; NBCCS; PTCH11
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Patched, Antibody; Patched Antibody; DROSOPHILA HOMOLOG OF 1; patched homolog (Drosophila); anti-Patched antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total Patched protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1447
Applicable Applications for anti-Patched antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from human Patched.
Target Name
Patched
Preparation and Storage
Store at -20 degree C
WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells (Lane 2) and HepG2 cells (Lane 3), using Patched antiobdy. The lane on the left is treated with synthesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells (Lane 2) and HepG2 cells (Lane 3), using Patched antiobdy. The lane on the left is treated with synthesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from mouse muscle cells, using Patched antibody.)
WB (Western Blot)
(Western blot analysis of extracts from mouse muscle cells, using Patched antibody.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using Patched antibody.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using Patched antibody.)
Related Product Information for anti-Patched antibody
Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.Trudy G. Oliver, Development, May 2005; 132: 2425 - 2439. Florence Brellier, Cancer Res., Apr 2004; 64: 2699 - 2704. Heidi Hahn, J. Biol. Chem., May 1996; 271: 12125. RL Johnson, Development, Dec 1995; 121: 4161.
Product Categories/Family for anti-Patched antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
144,356 Da
NCBI Official Full Name
protein patched homolog 1 isoform L
NCBI Official Synonym Full Names
patched 1
NCBI Official Symbol
PTCH1
NCBI Official Synonym Symbols
PTC; BCNS; HPE7; PTC1; PTCH; NBCCS; PTCH11
NCBI Protein Information
protein patched homolog 1
UniProt Protein Name
Protein patched homolog 1
UniProt Gene Name
PTCH1
UniProt Synonym Gene Names
PTCH; PTC; PTC1
UniProt Entry Name
PTC1_HUMAN
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Product Notes
The Patched ptch1 (Catalog #AAA303493) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Patched Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Patched can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Patched ptch1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Patched, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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