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IHC (Immunohistochemistry)
(PAX7 Antibody-Anti-PAX7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
Rabbit anti-Mouse, Human PAX7 Polyclonal Antibody | anti-PAX7 antibody
PAX7 Rabbit anti-Human Polyclonal (aa167-216) Antibody
Gene Names
PAX7; HUP1; RMS2; PAX7B
Reactivity
Mouse, Human
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
PAX7, Antibody; PAX7 Rabbit anti-Human Polyclonal (aa167-216) Antibody; PathPlus PAX7 Antibody (aa167-216); PAX7; HUP1; Paired box 7; Paired box gene 7; Paired box homeotic gene 7; Paired box protein Pax-7; RMS2; Paired domain gene 7; PAX7 transcriptional factor; PAX7B; anti-PAX7 antibody
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human PAX7
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5mg/ml (varies by lot)
Applicable Applications for anti-PAX7 antibody
WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Target
Human PAX7
Immunogen
Synthetic peptide located between aa167-216 of human PAX7 (P23759, NP_002575). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Guinea pig, Turkey, Zebra finch, Chicken (100%); Xenopus, Salmon, Zebrafish (92%).
Conjugation
Unconjugated
Epitope
aa167-216
Preparation and Storage
Short term: Store at 2-8 degree C. Long term: Aliquot and store at -20 degree C. Avoid freeze/thaw cycles.
IHC (Immunohistochemistry)
(PAX7 Antibody-Anti-PAX7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
IHC (Immunohistochemistry)
(PAX7 Antibody-Anti-PAX7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
IHC (Immunohistochemisry)
(PAX7 Antibody-Anti-PAX7 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
IHC (Immunohistochemisry)
(PAX7 Antibody-Anti-PAX7 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
IHC (Immunohiostchemistry)
(PAX7 Antibody-Anti-PAX7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
IHC (Immunohiostchemistry)
(PAX7 Antibody-Anti-PAX7 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
WB (Western Blot)
(PAX7 Antibody-Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
WB (Western Blot)
(PAX7 Antibody-Jurkat Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.)
Related Product Information for anti-PAX7 antibody
PAX7 antibody is an unconjugated rabbit polyclonal antibody to PAX7 (aa167-216) from human. It is reactive with human and mouse. Validated for IHC and WB.
PAX7 is a paired box transcription factor involved in fetal development and carcinogenesis. It is thought to be involved in tumor suppression, as PAX7 gene fusions with the forkhead transcription factor FOXO1 are associated with and prognostic for alveolar rhabdomyosarcoma. In the developing nervous system, PAX7 expression guides cell fate and morphology in the neuroepithelial layer and promotes the differentiation of neural progenitor cells into neurons. In immunohistochemistry, PAX7 has high nuclear positivity in skeletal muscle and in the tongue. In the brain and central nervous system, it has moderate expression in the cerebral cortex, midbrain, pons and medulla, and lower levels of positivity in the hippocampus, amygdala, basal ganglia, hypothalamus and spinal cord, and some positivity in the epididymis.
PAX7 is a paired box transcription factor involved in fetal development and carcinogenesis. It is thought to be involved in tumor suppression, as PAX7 gene fusions with the forkhead transcription factor FOXO1 are associated with and prognostic for alveolar rhabdomyosarcoma. In the developing nervous system, PAX7 expression guides cell fate and morphology in the neuroepithelial layer and promotes the differentiation of neural progenitor cells into neurons. In immunohistochemistry, PAX7 has high nuclear positivity in skeletal muscle and in the tongue. In the brain and central nervous system, it has moderate expression in the cerebral cortex, midbrain, pons and medulla, and lower levels of positivity in the hippocampus, amygdala, basal ganglia, hypothalamus and spinal cord, and some positivity in the epididymis.
References
J Clin Oncol. 2002 Jun 1;20(11):2672-9, PMID: 12039929; Bol Med Hosp Infant Mex. 2016 Nov-Dec;73(6):405-410, PMID: 29421285; J Comp Neurol. 2016 Apr 1;524(5):940-62, PMID: 26287727;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,119 Da
NCBI Official Full Name
Homo sapiens paired box 7 (PAX7), transcript variant 1, mRNA
NCBI Official Synonym Full Names
paired box 7
NCBI Official Symbol
PAX7
NCBI Official Synonym Symbols
HUP1; RMS2; PAX7B
NCBI Protein Information
paired box protein Pax-7; PAX7 transcriptional factor; paired box homeotic gene 7; paired domain gene 7
UniProt Protein Name
Paired box protein Pax-7
UniProt Gene Name
PAX7
UniProt Synonym Gene Names
HUP1
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Product Notes
The PAX7 pax7 (Catalog #AAA162487) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAX7 Rabbit anti-Human Polyclonal (aa167-216) Antibody reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's PAX7 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PAX7 pax7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAX7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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