WB (Western Blot)
Rabbit PDE4D3 Polyclonal Antibody | anti-PDE4D3 antibody
PDE4D3 Antibody
Gene Names
PDE2A; PDE2A1; PED2A4; cGSPDE; CGS-PDE
Reactivity
Chicken, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, ELISA
Synonyms
PDE4D3, Antibody; PDE4D3 Antibody; DPDE3; hPDE4D3; HSPDE4D; PDE43; PDE4D; PDE4DN2; Phosphodiesterase 4D; Phosphodiesterase 4D cAMP-specific; Phosphodiesterase Type 4D3; STRK1 antibody; anti-PDE4D3 antibody
Host
Rabbit
Reactivity
Chicken, Mouse, Rat
Clonality
Polyclonal
Specificity
This antibody does not cross react with PDE4D1, PDE4D2, PDE4D4, PDE4D5. Does not cross react with other PDE family members such as PDE4A, PDE4B or PDE4C.
Form/Format
Affinity Purified
Concentration
0.68 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
941
Applicable Applications for anti-PDE4D3 antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, CM (Confocal Microscopy)
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on PDE4D3 variant.
Expression
Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
Molecular Function
Hydrolase, 3', 5'-cyclic-AMP phosphodiesterase activity, cAMP binding
Structure
Homodimer for the long isoforms. Isoforms with truncated N-termini are monomeric. Isoform 3 is part of a ternary complex containing PRKAR2A, PRKAR2B and AKAP9. Interacts with PDE4DIP. Identified in a complex composed of RYR1, PDE4D, PKA, FKBP1A and protein phosphatase 1 (PP1).
Subcellular Location
Apical cell membrane, Cytoplasm, Membrane
Preparation and Storage
-20 degree C for long term storage
WB (Western Blot)
WB (Western Blot)
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-PDE4D3 antibody
Affinity Purified cAMP-specific phoshodiesterase HPDE4D3 variant Antibody
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Product Categories/Family for anti-PDE4D3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
87,235 Da
NCBI Official Full Name
phosphodiesterase 2A, cGMP-stimulated, isoform CRA_a
NCBI Official Synonym Full Names
phosphodiesterase 2A
NCBI Official Symbol
PDE2A
NCBI Official Synonym Symbols
PDE2A1; PED2A4; cGSPDE; CGS-PDE
NCBI Protein Information
cGMP-dependent 3',5'-cyclic phosphodiesterase
UniProt Protein Name
cGMP-dependent 3',5'-cyclic phosphodiesterase
UniProt Gene Name
PDE2A
UniProt Synonym Gene Names
CGS-PDE; cGSPDE
UniProt Entry Name
PDE2A_HUMAN
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Product Notes
The PDE4D3 pde2a (Catalog #AAA76000) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE4D3 Antibody reacts with Chicken, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDE4D3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, CM (Confocal Microscopy). Researchers should empirically determine the suitability of the PDE4D3 pde2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE4D3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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