WB (Western Blot)
(Western blot analysis of lysate from mouse kidney tissue lysate, using PDGFD Antibody. AAA284895 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Rabbit anti-Mouse PDGFD Polyclonal Antibody | anti-PDGFD antibody
PDGFD Antibody
Gene Names
PDGFD; IEGF; SCDGFB; MSTP036; SCDGF-B
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PDGFD, Antibody; PDGFD Antibody; Platelet-derived growth factor D; PDGF-D; Iris-expressed growth factor; Spinal cord-derived growth factor B; SCDGF-B; latent form; PDGFD latent form; receptor-binding form; PDGFD receptor-binding form; PDGFD; IEGF; SCDGFB; anti-PDGFD antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PDGFD antibody is generated from a rabbit immunized with a recombinant protein of human PDGFD.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
364
Applicable Applications for anti-PDGFD antibody
ELISA, WB (Western Blot)
Calculated MW
42848
Function
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).
Cellular location
Secreted. Note=Released by platelets upon wounding
Tissue location
Tissue Location Expressed at high levels in the heart, pancreas, adrenal gland and ovary and at low levels in placenta, liver, kidney, prostate,testis, small intestine, spleen and colon. Inthe kidney, expressed by the visceralepithelial cells of the glomeruli. A widespreadexpression is also seen in the medial smoothmuscle cells of arteries and arterioles, as well as in smooth muscle cells of vasa rectae inthe medullary area Expressed in the adventitial connective tissue surrounding the suprarenal artery. In chronic obstructive nephropathy, a persistent expression is seen in glomerular visceral epithelial cells and vascular smooth muscle cells, as well as de novo expression by periglomerular interstitial cells and by some neointimal cells of atherosclerotic vessels. Expression in normal prostate is seen preferentially in the mesenchyme of the gland while expression is increased and more profuse in prostate carcinoma. Expressed in many ovarian, lung, renal and brain cancer-derived cell lines.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of lysate from mouse kidney tissue lysate, using PDGFD Antibody. AAA284895 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
WB (Western Blot)
(Western blot analysis of lysate from mouse kidney tissue lysate, using PDGFD Antibody. AAA284895 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.)
Related Product Information for anti-PDGFD antibody
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).
Product Categories/Family for anti-PDGFD antibody
References
Hamada T.,et al.Biochem. Biophys. Res. Commun. 280:733-737(2001).
Bergsten E.,et al.Nat. Cell Biol. 3:512-516(2001).
LaRochelle W.J.,et al.Nat. Cell Biol. 3:517-521(2001).
Wistow G.,et al.Mol. Vis. 8:185-195(2002).
Liu B.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
Bergsten E.,et al.Nat. Cell Biol. 3:512-516(2001).
LaRochelle W.J.,et al.Nat. Cell Biol. 3:517-521(2001).
Wistow G.,et al.Mol. Vis. 8:185-195(2002).
Liu B.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
platelet-derived growth factor D isoform 1
NCBI Official Synonym Full Names
platelet derived growth factor D
NCBI Official Symbol
PDGFD
NCBI Official Synonym Symbols
IEGF; SCDGFB; MSTP036; SCDGF-B
NCBI Protein Information
platelet-derived growth factor D
UniProt Protein Name
Platelet-derived growth factor D
UniProt Gene Name
PDGFD
UniProt Synonym Gene Names
IEGF; SCDGFB; PDGF-D; SCDGF-B; PDGFD latent form; PDGFD receptor-binding form
UniProt Entry Name
PDGFD_HUMAN
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Product Notes
The PDGFD pdgfd (Catalog #AAA284895) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDGFD Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PDGFD can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PDGFD pdgfd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDGFD, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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