Rabbit anti-Human, Mouse PDZD3 Polyclonal Antibody | anti-PDZD3 antibody

PDZD3 Antibody

Cat. Num. AAA232940

• Gene Names: PDZD3; IKEPP; PDZK2; NHERF4
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
• Synonyms: PDZD3, Antibody; PDZD3 Antibody; Na(+)/H(+) exchange regulatory cofactor NHE-RF4; NHERF-4; Intestinal and kidney-enriched PDZ protein; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2; Na/Pi cotransporter C-terminal-associated protein 2; NaPi-Cap2; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Sodium-hydrogen exchanger regulatory factor 4; PDZD3; IKEPP; NHERF4; PDZK2; DLNB27; anti-PDZD3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Caprylic Acid Ammonium Sulfate Precipitation purified
• Form/Format: Liquid
• Sequence Length: 505

• Applicable Applications for anti-PDZD3 antibody: IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Immunogen: Recombinant human Na(+)/H(+) exchange regulatory cofactor NHE-RF4 protein (42-291AA)
• Preservative: 0.03% Proclin 300
• Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Conjugation: Non-conjugated
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-82687 / sc-82689
• Preparation and Storage: Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human kidney using AAA232940 at dilution 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human skin using AAA232940 at dilution 1:100)

WB (Western Blot)

(Western blotAll lanes: PDZD3 antibody at 2ug/mlLane 1:mouse kidney tissueLane 2:mouse heart tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 62,55,53,42,25 kDaObserved band size: 61 kDa)

Related Product Information for anti-PDZD3 antibody

Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.

References

[1]"Complete sequencing and characterization of 21, 243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36: 40-45(2004). [2]"Human chromosome 11 DNA sequence and analysis including novel gene identification."Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. Sakaki Y. Nature 440: 497-500(2006). [3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."The MGC Project TeamGenome Res. 14: 2121-2127(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 270483764
• NCBI GeneID: 79849
• NCBI Accession #: NP_001161940.1
• NCBI GenBank Nucleotide #: NM_001168468.1
• UniProt Accession #: Q86UT5; Q8N6R4; Q8NAW7; Q8NEX7; Q9H5Z3
• Molecular Weight: 24,105 Da
• NCBI Official Full Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF4 isoform 1
• NCBI Official Synonym Full Names: PDZ domain containing 3
• NCBI Official Symbol: PDZD3
• NCBI Official Synonym Symbols: IKEPP; PDZK2; NHERF4
• NCBI Protein Information: Na(+)/H(+) exchange regulatory cofactor NHE-RF4
• UniProt Protein Name: Na(+)/H(+) exchange regulatory cofactor NHE-RF4
• UniProt Gene Name: PDZD3
• UniProt Synonym Gene Names: IKEPP; NHERF4; PDZK2; NHERF-4; Na/Pi cotransporter C-terminal-associated protein 2; NaPi-Cap2
• UniProt Entry Name: NHRF4_HUMAN