IF (Immunofluorescence)
(Immunofluorescence of Pellino 1 in HepG2 cells with Pellino 1 antibody at 20 μg/ml.)
Rabbit Pellino 1 Polyclonal Antibody | anti-PELI1 antibody
Pellino 1 Antibody
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
Pellino 1 Antibody is affinity chromatography purified via peptide column.
Synonyms
Pellino 1, Antibody; Pellino 1 Antibody; Pellino 1; PRISM; E3 ubiquitin-protein ligase pellino homolog 1; Pellino-related intracellular-signaling molecule; Pellino-1; pellino E3 ubiquitin protein ligase 1; anti-PELI1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Pellino 1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
418
Applicable Applications for anti-PELI1 antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal Pellino 1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Pellino 1.
Buffer
Pellino 1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Pellino 1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of Pellino 1 in HepG2 cells with Pellino 1 antibody at 20 μg/ml.)
IF (Immunofluorescence)
(Immunofluorescence of Pellino 1 in HepG2 cells with Pellino 1 antibody at 20 μg/ml.)
ICC (Immunocytochemistry)
(Immunocytochemistry of Pellino in HepG2 cells with Pellino 1 antibody at 2.5 μg/ml.)
ICC (Immunocytochemistry)
(Immunocytochemistry of Pellino in HepG2 cells with Pellino 1 antibody at 2.5 μg/ml.)
WB (Western Blot)
(Western blot analysis of Pellino 1 in human liver tissue lysate with Pellino 1 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of Pellino 1 in human liver tissue lysate with Pellino 1 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-PELI1 antibody
Pellino 1 Antibody: The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors. Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex, ultimately resulting in the activation of NF-κB. Like other members of the Pellino family, Pellino 1 is an E3 ubiquitin ligase, able to catalyze the polyubiquitination of IRAK1. It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-ε and TBK1. In addition to phosphorylation, Pellino 1 activity is also modulated via ubiquitination and sumoylation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46 kDa
NCBI Official Full Name
E3 ubiquitin-protein ligase pellino homolog 1
NCBI Official Synonym Full Names
pellino E3 ubiquitin protein ligase 1
NCBI Official Symbol
PELI1
NCBI Protein Information
E3 ubiquitin-protein ligase pellino homolog 1; pellino-1; protein pellino homolog 1; pellino-related intracellular-signaling molecule
UniProt Protein Name
E3 ubiquitin-protein ligase pellino homolog 1
UniProt Gene Name
PELI1
UniProt Synonym Gene Names
PRISM; Pellino-1
UniProt Entry Name
PELI1_HUMAN
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Product Notes
The PELI1 peli1 (Catalog #AAA40618) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Pellino 1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Pellino 1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PELI1 peli1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pellino 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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