IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded Human spleen tissue using Perforin 1 Polyclonal Antibody at dilution of 1:200.)
Rabbit anti-Human Perforin 1 Polyclonal Antibody | anti-P1 antibody
Perforin 1 Polyclonal Antibody
Gene Names
PRF1; P1; PFP; HPLH2
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Affinity Purification
Synonyms
Perforin 1, Antibody; Perforin 1 Polyclonal Antibody; Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP); anti-P1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
555
Applicable Applications for anti-P1 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Synthesized peptide derived from Perforin 1
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol pH 7.4.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded Human spleen tissue using Perforin 1 Polyclonal Antibody at dilution of 1:200.)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded Human spleen tissue using Perforin 1 Polyclonal Antibody at dilution of 1:200.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human kidney tissue using Perforin 1 Polyclonal Antibody at dilution of 1:200.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human kidney tissue using Perforin 1 Polyclonal Antibody at dilution of 1:200.)
WB (Western Blot)
(Western Blot analysis of Hela cells using Perforin 1 Polyclonal Antibody at dilution of 1:500.)
WB (Western Blot)
(Western Blot analysis of Hela cells using Perforin 1 Polyclonal Antibody at dilution of 1:500.)
Related Product Information for anti-P1 antibody
PRF1 (Perforin 1) is a Protein Coding gene. Diseases associated with PRF1 include Hemophagocytic Lymphohistiocytosis, Familial, 2 and Lymphoma, Non-Hodgkin. Among its related pathways are Allograft rejection and Apoptosis and survival Caspase cascade. GO annotations related to this gene include calcium ion binding and wide pore channel activity. The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated Molecular Weight: 61kDa
Observed Molecular Weight: 61kDa
Observed Molecular Weight: 61kDa
NCBI Official Full Name
perforin-1
NCBI Official Synonym Full Names
perforin 1
NCBI Official Symbol
PRF1
NCBI Official Synonym Symbols
P1; PFP; HPLH2
NCBI Protein Information
perforin-1
UniProt Protein Name
Perforin-1
UniProt Gene Name
PRF1
UniProt Synonym Gene Names
PFP; P1; PFP
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Product Notes
The P1 prf1 (Catalog #AAA173836) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Perforin 1 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Perforin 1 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the P1 prf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Perforin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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