Rabbit anti-Human, Mouse PI3K gamma/Pik3cg Polyclonal Antibody | anti-Pik3cg antibody

Anti-PI3K gamma/Pik3cg Antibody, Rabbit Polyclonal

Cat. Num. AAA254419

• Gene Names: PIK3CG; PI3K; PIK3; PI3CG; PI3Kgamma
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Protein A & Antigen Affinity
• Synonyms: PI3K gamma/Pik3cg, Antibody; Anti-PI3K gamma/Pik3cg Antibody, Rabbit Polyclonal; PIK3CG/PI3K Antibody, Rabbit PAb, Antigen Affinity Purified; anti-Pik3cg antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: Human PI3K gamma/Pik3cg
• Purity/Purification: Protein A & Antigen Affinity
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-Pik3cg antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: A synthetic peptide corresponding to the C-terminus of the Human PIK3CG/PI3K
• Conjugation: Unconjugated
• Preparation: Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human PIK3CG/PI3K, and purified by antigen affinity chromatography.
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

IHC (Immunohistochemistry)

(Immunochemical staining CK14 in rat skin with rabbit polyclonal antibody (1:2500, formalin-fixed paraffin embedded sections).)

IHC (Immunohistochemistry)

(Immunochemical staining PIK3CG in mouse liver with rabbit polyclonal antibody (1:2500, formalin-fixed paraffin embedded sections).)

IHC (Immunohistochemisry)

(Immunochemical staining PIK3CG in human kidney with rabbit polyclonal antibody (1:2500, formalin-fixed paraffin embedded sections).)

IHC (Immunohiostchemistry)

(Immunochemical staining PIK3CG in human liver with rabbit polyclonal antibody (1:2500, formalin-fixed paraffin embedded sections).)

WB (Western Blot)

(Anti-PIK3CG rabbit polyclonal antibody at 1:500 dilutionLane A: Jurkat Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti- Rabbit  IgG H&L (Dylight 800)  at 1/10000 dilution.Developed using the Odyssey technique.Performed under reducing conditions.Predicted band size:126 kDaObserved band size:126 kDa)

Related Product Information for anti-Pik3cg antibody

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p11-alpha p11-beta, and p11-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

Product Categories/Family for anti-Pik3cg antibody

Common G-Chain signaling pathway

References

Kachele M, Hennige AM, Machann J, et al. Variation in the Phosphoinositide 3-Kinase Gamma Gene Affects Plasma HDL-Cholesterol without Modification of Metabolic or Inflammatory Markers. Zhang Y, ed. PLoS ONE. 2015;10(12):e0144494.

NCBI and Uniprot Product Information

• NCBI GI #: 21237725
• NCBI GeneID: 5294
• NCBI Accession #: NP_002640.2
• NCBI GenBank Nucleotide #: NM_002649.2
• UniProt Accession #: P48736; Q8IV23; Q9BZC8; A4D0Q6
• Molecular Weight: 126,454 Da
• NCBI Official Full Name: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
• NCBI Official Synonym Full Names: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
• NCBI Official Symbol: PIK3CG
• NCBI Official Synonym Symbols: PI3K; PIK3; PI3CG; PI3Kgamma
• NCBI Protein Information: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; p110gamma; p120-PI3K; PI3K-gamma; p110-gamma; PI3-kinase subunit gamma; ptdIns-3-kinase subunit gamma; 1-phosphatidylinositol 3-kinase; ptdIns-3-kinase subunit p110-gamma; ser
• UniProt Protein Name: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
• UniProt Gene Name: PIK3CG
• UniProt Synonym Gene Names: PI3-kinase subunit gamma; PI3K-gamma; PI3Kgamma; PtdIns-3-kinase subunit gamma; PtdIns-3-kinase subunit p110-gamma; p110gamma
• UniProt Entry Name: PK3CG_HUMAN