IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Rabbit anti-Human PI3KC2G Polyclonal Antibody | anti-PIK3C2G antibody
PI3KC2G Antibody (N-term)
Gene Names
PIK3C2G; PI3K-C2GAMMA; PI3K-C2-gamma
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PI3KC2G, Antibody; PI3KC2G Antibody (N-term); Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; PI3K-C2-gamma; PtdIns-3-kinase C2 subunit gamma; Phosphoinositide 3-kinase-C2-gamma; PIK3C2G; anti-PIK3C2G antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PI3KC2G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-123 amino acids from the N-terminal region of human PI3KC2G.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Sequence Positions
93-123
Sequence Length
1445
Applicable Applications for anti-PIK3C2G antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
Generates phosphatidylinositol 3-phosphate(PtdIns3P) and phosphatidylinositol3,4-bisphosphate (PtdIns(3,4)P2) that act assecond messengers. May play a role in SDF1A-stimulated chemotaxis (By similarity).
Cellular Location
Membrane; Peripheral membrane protein.
Tissue Location
Highly expressed in liver, prostate and testis.Lower levels in small intestine, kidney and pancreasoncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid bindingmotifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
WB (Western Blot)
(Western blot analysis of PI3KC2G antibody (N-term) in CEM cell line lysates (35ug/lane). PI3KC2G (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of PI3KC2G antibody (N-term) in CEM cell line lysates (35ug/lane). PI3KC2G (arrow) was detected using the purified Pab.)
Related Product Information for anti-PIK3C2G antibody
PI3KC2G belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined.
Product Categories/Family for anti-PIK3C2G antibody
References
Rozycka, M., et al., Genomics 54(3):569-574 (1998).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
165715
NCBI Official Full Name
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform 3
NCBI Official Synonym Full Names
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
NCBI Official Symbol
PIK3C2G
NCBI Official Synonym Symbols
PI3K-C2GAMMA; PI3K-C2-gamma
NCBI Protein Information
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
UniProt Protein Name
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma
UniProt Gene Name
PIK3C2G
UniProt Synonym Gene Names
PI3K-C2-gamma; PtdIns-3-kinase C2 subunit gamma
UniProt Entry Name
P3C2G_HUMAN
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Product Notes
The PIK3C2G pik3c2g (Catalog #AAA286050) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 93-123. The PI3KC2G Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PI3KC2G can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PIK3C2G pik3c2g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PI3KC2G, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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