IHC (Immunohiostchemistry)
(Immunohistochemistry of PIAS3 in human breast carcinoma tissue with PIAS3 antibody at 5 μg/mL.)
Rabbit PIAS3 Polyclonal Antibody | anti-PIAS3 antibody
PIAS3 Antibody
Gene Names
PIAS3; ZMIZ5
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
PIAS3 Antibody is affinity chromatography purified via peptide column.
Synonyms
PIAS3, Antibody; PIAS3 Antibody; PIAS3; ZMIZ5; E3 SUMO-protein ligase PIAS3; Protein inhibitor of activated STAT protein 3; protein inhibitor of activated STAT, 3; anti-PIAS3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
PIAS3 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
628
Applicable Applications for anti-PIAS3 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
PIAS3 antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human PIAS3.
Buffer
PIAS3 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
PIAS3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of PIAS3 in human breast carcinoma tissue with PIAS3 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of PIAS3 in human breast carcinoma tissue with PIAS3 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of PIAS3 in K562 cell lysate with PIAS3 antibody at 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of PIAS3 in K562 cell lysate with PIAS3 antibody at 1 μg/mL.)
Related Product Information for anti-PIAS3 antibody
PIAS3 Antibody: The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS3. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS3 binds specifically to STAT3 following the stimulation of STAT3. Increased expression of PIAS3 has been observed in several human cancers, including lung, breast, and brain tumors, but not in anaplastic lymphoma kinase-positive T/null-cell lymphomas, indicating that PIAS3 plays multiple roles in different tissue and cell types.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68,017 Da
NCBI Official Full Name
E3 SUMO-protein ligase PIAS3
NCBI Official Synonym Full Names
protein inhibitor of activated STAT, 3
NCBI Official Symbol
PIAS3
NCBI Official Synonym Symbols
ZMIZ5
NCBI Protein Information
E3 SUMO-protein ligase PIAS3; zinc finger, MIZ-type containing 5; protein inhibitor of activated STAT protein 3
UniProt Protein Name
E3 SUMO-protein ligase PIAS3
UniProt Gene Name
PIAS3
UniProt Entry Name
PIAS3_HUMAN
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Product Notes
The PIAS3 pias3 (Catalog #AAA40042) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIAS3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PIAS3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PIAS3 pias3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIAS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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