ICC (Immunocytochemistry)
(Immunocytochemistry staining of HeLa using PID antibody at 10 ug/mL.)
Rabbit PID Polyclonal Antibody | anti-PID antibody
PID Antibody
Gene Names
MTA2; PID; MTA1L1
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
DEAE purified
Synonyms
PID, Antibody; PID Antibody; PID, MTA2; anti-PID antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
No cross response to MTA1.
Purity/Purification
DEAE purified
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
668
Applicable Applications for anti-PID antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a synthetic peptide corresponding to amino acids 652 to 668 of human PID (6), which differ from the mouse sequence by one amino acid.
Target Name
PID
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry staining of HeLa using PID antibody at 10 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry staining of HeLa using PID antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of PID expression in HeLa whole cell lysates in the absence (A) or presence (B) of blocking peptide with PID antibody at 1 ug /ml.)
WB (Western Blot)
(Western blot analysis of PID expression in HeLa whole cell lysates in the absence (A) or presence (B) of blocking peptide with PID antibody at 1 ug /ml.)
Related Product Information for anti-PID antibody
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 pathway, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. The transcriptional activity of p53 is modulated by protein stability and acetylation. PID/MTA2, also termed MTA1-L1, was found to be a subunit of nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is ubiquitously expressed in human tissues.
Product Categories/Family for anti-PID antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
55,037 Da
NCBI Official Full Name
p53 target protein in deacetylase complex
NCBI Official Synonym Full Names
metastasis associated 1 family, member 2
NCBI Official Symbol
MTA2
NCBI Official Synonym Symbols
PID; MTA1L1
NCBI Protein Information
metastasis-associated protein MTA2
UniProt Protein Name
Metastasis-associated protein MTA2
UniProt Gene Name
MTA2
UniProt Synonym Gene Names
MTA1L1; PID; MTA1-L1 protein
UniProt Entry Name
MTA2_HUMAN
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Product Notes
The PID mta2 (Catalog #AAA304334) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PID Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PID can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PID mta2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PID, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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