WB (Western Blot)
(Western blot analysis of lysates from mouse brain and rat brain tissue lysate(from left to right), using PIP4K2C Antibody (N-term). AAA284977 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Rabbit PIP4K2C Polyclonal Antibody | anti-PIP4K2C antibody
PIP4K2C Antibody (N-term)
Gene Names
PIP4K2C; PIP5K2C
Reactivity
Mouse, rat (Predicted Reactivity: Bovine)
Applications
ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PIP4K2C, Antibody; PIP4K2C Antibody (N-term); Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; Phosphatidylinositol 5-phosphate 4-kinase type II gamma; PI(5)P 4-kinase type II gamma; PIP4KII-gamma; PIP4K2C; PIP5K2C; anti-PIP4K2C antibody
Host
Rabbit
Reactivity
Mouse, rat (Predicted Reactivity: Bovine)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PIP4K2C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-57amino acids from the N-terminal region of human PIP4K2C.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
403
Applicable Applications for anti-PIP4K2C antibody
ELISA, WB (Western Blot)
Function
Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May bea GTP sensor, has higher GTP-dependent kinase activity that ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic- independent mechanism. They interact with PIP5Ks and suppress PIP5K mediated PtdIns (4.5) p2 synthesis and insulin- dependent conversion to PTdInns (3,4,5). P3.
Function
May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum.
Cellular Location
Cytoplasm. Membrane. Note=Mostly found in the cytosol and surrounding plasma membrane. However, its presence in the endoplasmic reticulum seems to be a prerequisite for PIP2 synthesis (By similarity).
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of lysates from mouse brain and rat brain tissue lysate(from left to right), using PIP4K2C Antibody (N-term). AAA284977 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
WB (Western Blot)
(Western blot analysis of lysates from mouse brain and rat brain tissue lysate(from left to right), using PIP4K2C Antibody (N-term). AAA284977 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Related Product Information for anti-PIP4K2C antibody
May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum (By similarity).
Product Categories/Family for anti-PIP4K2C antibody
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Daub H.,et al.Mol. Cell 31:438-448(2008).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
Scherer S.E.,et al.Nature 440:346-351(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Daub H.,et al.Mol. Cell 31:438-448(2008).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW:47300
NCBI Official Full Name
phosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform a
NCBI Official Synonym Full Names
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
NCBI Official Symbol
PIP4K2C
NCBI Official Synonym Symbols
PIP5K2C
NCBI Protein Information
phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
UniProt Protein Name
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
UniProt Gene Name
PIP4K2C
UniProt Synonym Gene Names
PIP5K2C; PI(5)P 4-kinase type II gamma; PIP4KII-gamma
UniProt Entry Name
PI42C_HUMAN
Similar Products
Product Notes
The PIP4K2C pip4k2c (Catalog #AAA284977) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIP4K2C Antibody (N-term) reacts with Mouse, rat (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's PIP4K2C can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PIP4K2C pip4k2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIP4K2C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.