IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Rabbit PIP5K2 Alpha (PIP5K2A) Polyclonal Antibody | anti-PIP4K2A antibody
PIP5K2 Alpha (PIP5K2A) Antibody (C-term)
Gene Names
PIP4K2A; PIPK; PI5P4KA; PIP5K2A; PIP5KIIA; PIP5KII-alpha
Reactivity
Human (Predicted Reactivity: Mouse, Pig, Rat)
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PIP5K2 Alpha (PIP5K2A), Antibody; PIP5K2 Alpha (PIP5K2A) Antibody (C-term); Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; 1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; Diphosphoinositide kinase 2-alpha; PIP5KIII; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PI(5)P 4-kinase type II alpha; PIP4KII-alpha; PtdIns(4)P-5-kinase B isoform; PtdIns(4)P-5-kinase C isoform; PtdIns(5)P-4-kinase isoform 2-alpha; PIP4K2A; PIP5K2; PIP5K2A; anti-PIP4K2A antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Pig, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PIP5K2 Alpha (PIP5K2A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-335 amino acids from the C-terminal region of human PIP5K2 Alpha (PIP5K2A).
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 1.83 (varies by lot)
Sequence Positions
303-335
Sequence Length
406
Applicable Applications for anti-PIP4K2A antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
WB (Western Blot)
(Western blot analysis of anti-PIP5K2A Pab in HL60 cell lysate. PIP5K2A (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.)
WB (Western Blot)
(Western blot analysis of anti-PIP5K2A Pab in HL60 cell lysate. PIP5K2A (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.)
Related Product Information for anti-PIP4K2A antibody
Phosphatidylinositol-4,5-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. TPIP5K2A is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-4-phosphate on the fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol-4,5-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. The protein is a member of the phosphatidylinositol-4-phosphate 5-kinase family.
Product Categories/Family for anti-PIP4K2A antibody
References
Rozenvayn, N., et al., J. Biol. Chem. 278(10):8126-8134 (2003).
Boronenkov, I.V., et al., J. Biol. Chem. 270(7):2881-2884 (1995).
Loijens, J.C., et al., Adv. Enzyme Regul. 36, 115-140 (1996).
Divecha, N., et al., Biochem. J. 309 (Pt 3), 715-719 (1995).
Boronenkov, I.V., et al., J. Biol. Chem. 270(7):2881-2884 (1995).
Loijens, J.C., et al., Adv. Enzyme Regul. 36, 115-140 (1996).
Divecha, N., et al., Biochem. J. 309 (Pt 3), 715-719 (1995).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46225
NCBI Official Full Name
phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
NCBI Official Synonym Full Names
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
NCBI Official Symbol
PIP4K2A
NCBI Official Synonym Symbols
PIPK; PI5P4KA; PIP5K2A; PIP5KIIA; PIP5KII-alpha
NCBI Protein Information
phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
UniProt Protein Name
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
UniProt Gene Name
PIP4K2A
UniProt Synonym Gene Names
PIP5K2; PIP5K2A; PI(5)P 4-kinase type II alpha; PIP4KII-alpha
UniProt Entry Name
PI42A_HUMAN
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Product Notes
The PIP4K2A pip4k2a (Catalog #AAA284678) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 303-335. The PIP5K2 Alpha (PIP5K2A) Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse, Pig, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's PIP5K2 Alpha (PIP5K2A) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the PIP4K2A pip4k2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIP5K2 Alpha (PIP5K2A), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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