WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.)
Rabbit anti-Human PIPK I gamma Polyclonal Antibody | anti-PIPKIgamma antibody
PIPK I gamma Polyclonal Antibody
Gene Names
PIP5K1C; LCCS3; PIPKIg_v4; PIP5Kgamma; PIP5K-GAMMA
Reactivity
Human
Applications
Western Blot
Synonyms
PIPK I gamma, Antibody; PIPK I gamma Polyclonal Antibody; PIP5K1C; KIAA0589; Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; PtdIns (4)P-5-kinase 1 gamma; Phosphatidylinositol 4-phosphate 5-kinase type I gamma; PIP5KIgamma; anti-PIPKIgamma antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Applicable Applications for anti-PIPKIgamma antibody
WB (Western Blot)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.)
WB (Western Blot)
(Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.)
Related Product Information for anti-PIPKIgamma antibody
Catalyzes the phosphorylation of phosphatidylinositol 4- phosphate (PtdIns4P) to form phosphatidylinositol 4, 5-bisphosphate (PtdIns (4, 5)P2). PtdIns (4, 5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3, 4, 5-trisphosphate (PtdIns (3, 4, 5)P3), another second messenger. The majority of PtdIns (4, 5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P. Participates in a variety of cellular processes such as vesicle mediated transport, cell adhesion, cell polarization and cell migration. Together with PIP5K1A is required for phagocytosis, but they regulate different types of actin remodeling at sequential steps. Promotes particle attachment by generating the pool of PtdIns (4, 5)P2 that induces controlled actin depolymerization to facilitate Fc-gamma-R clustering. Mediates RAC1-dependent reorganization of actin filaments. Required for synaptic vesicle transport. Controls the plasma membrane pool of PtdIns (4, 5)P2 implicated in synaptic vesicle endocytosis and exocytosis. Plays a role in endocytosis mediated by clathrin and AP-2 (adaptor protein complex 2). Required for clathrin-coated pits assembly at the synapse. Participates in cell junction assembly. Modulates adherens junctions formation by facilitating CDH1 trafficking. Required for focal adhesion dynamics. Modulates the targeting of talins (TLN1 and TLN2) to the plasma membrane and their efficient assembly into focal adhesions. Regulates the interaction between talins (TLN1 and TLN2) and beta-integrins. Required for uropodium formation and retraction of the cell rear during directed migration. Has a role in growth factor- stimulated directional cell migration and adhesion. Required for talin assembly into nascent adhesions forming at the leading edge toward the direction of the growth factor. Negative regulator of T-cell activation and adhesion. Negatively regulates integrin alpha-L/beta-2 (LFA-1) polarization and adhesion induced by T-cell receptor. Together with PIP5K1A has a role during embryogenesis and together with PIP5K1B may have a role immediately after birth.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
73,260 Da
NCBI Official Full Name
phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform 1
NCBI Official Synonym Full Names
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
NCBI Official Symbol
PIP5K1C
NCBI Official Synonym Symbols
LCCS3; PIPKIg_v4; PIP5Kgamma; PIP5K-GAMMA
NCBI Protein Information
phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; type I PIP kinase; diphosphoinositide kinase; ptdIns(4)P-5-kinase 1 gamma; phosphatidylinositol 4-phosphate 5-kinase type I gamma; phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
UniProt Protein Name
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma
UniProt Gene Name
PIP5K1C
UniProt Synonym Gene Names
KIAA0589; PIP5K1-gamma; PtdIns(4)P-5-kinase 1 gamma; PIP5KIgamma
UniProt Entry Name
PI51C_HUMAN
Similar Products
Product Notes
The PIPKIgamma pip5k1c (Catalog #AAA295606) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIPK I gamma Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PIPK I gamma can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the PIPKIgamma pip5k1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIPK I gamma, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.