IHC (Immunohiostchemistry)
(Immunohistochemistry of PIST in rat colon tissue with PIST antibody at 1 ug/mL.)
Rabbit anti-Human, Mouse PIST Polyclonal Antibody | anti-PIST antibody
PIST Antibody
Gene Names
GOPC; CAL; FIG; PIST; GOPC1; dJ94G16.2
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
PIST, Antibody; PIST Antibody; Golgi associated PDZ and coiled-coil motif containing, GOPC; anti-PIST antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
462
Applicable Applications for anti-PIST antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide from near the center of human PIST.
Target Name
PIST
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of PIST in rat colon tissue with PIST antibody at 1 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of PIST in rat colon tissue with PIST antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of PIST in PC-3 cell lysate with PIST antibody at (A) 1, (B) 2 and (C) 4 ug/mL.)
WB (Western Blot)
(Western blot analysis of PIST in PC-3 cell lysate with PIST antibody at (A) 1, (B) 2 and (C) 4 ug/mL.)
Related Product Information for anti-PIST antibody
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). PIST, a PDZ-containing protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
Product Categories/Family for anti-PIST antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
35,130 Da
NCBI Official Full Name
PIST
NCBI Official Synonym Full Names
golgi-associated PDZ and coiled-coil motif containing
NCBI Official Symbol
GOPC
NCBI Official Synonym Symbols
CAL; FIG; PIST; GOPC1; dJ94G16.2
NCBI Protein Information
Golgi-associated PDZ and coiled-coil motif-containing protein
UniProt Protein Name
Golgi-associated PDZ and coiled-coil motif-containing protein
UniProt Gene Name
GOPC
UniProt Synonym Gene Names
CAL; FIG; PIST
UniProt Entry Name
GOPC_HUMAN
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Product Notes
The PIST gopc (Catalog #AAA307027) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIST Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PIST can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PIST gopc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIST, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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