WB (Western Blot)
(Western blot analysis of extracts from K562 cells, using PKR antibody and PKR antibody (Thr446) (Lanes 3 and 4))
Rabbit PKR Polyclonal Antibody | anti-PKR antibody
PKR Antibody (Thr446)
Applications
Immunohistochemistry, Western Blot
Purity
Affinity Chromatography
Synonyms
PKR, Antibody; PKR Antibody (Thr446); Rabbit Polyclonal PKR Antibody (Thr446); Polyclonal PKR antibody; Anti-PKR antibody; double stranded RNA activated protein kinase antibody; E2AK2 antibody; eIF-2A protein kinase 2 antibody; EIF2AK1 antibody; EIF2AK2 antibody; Eukaryotic translation initiation factor 2-alpha kinase 2 antibody; Interferon-induced double-stranded RNA-activated protein kinase antibody; interferon-inducible elF2alpha kinase antibody; Interferon-inducible RNA-dependent protein kinase antibody; MGC126524 antibody; P1/eIF-2A protein kinase antibody; p68 kinase antibody; PKR antibody; PRKR antibody; Protein kinase RNA-activated antibody; protein kinase interferon-inducible double stranded RNA dependent antibody; anti-PKR antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
PKR antibody (Thr446) detects endogenous levels of PKR only when phosphorylated at threonine 446
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Applicable Applications for anti-PKR antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
PKR antibody was raised in Rabbit using a synthesized phosphopeptide derived from human PKR around the phosphorylation site of threonine 446 (K-R-TP-R-S) as the immunogen.
Cross-Reactivity
Mouse
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
WB (Western Blot)
(Western blot analysis of extracts from K562 cells, using PKR antibody and PKR antibody (Thr446) (Lanes 3 and 4))
WB (Western Blot)
(Western blot analysis of extracts from K562 cells, using PKR antibody and PKR antibody (Thr446) (Lanes 3 and 4))
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using PKR antibody (Thr446))
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using PKR antibody (Thr446))
Related Product Information for anti-PKR antibody
PKR is a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.
Product Categories/Family for anti-PKR antibody
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Product Notes
The PKR (Catalog #AAA226115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PKR can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PKR for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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