IF (Immunofluorescence)
(Immunofluorescence of PLAC3 in HeLa cells with PLAC3 antibody at 20 μg/mL.)
Rabbit PLAC3 Polyclonal Antibody | anti-PAPPA2 antibody
PLAC3 Antibody
Gene Names
PAPPA2; PAPPE; PLAC3; PAPP-E; PAPP-A2
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
PLAC3 Antibody is affinity chromatography purified via peptide column.
Synonyms
PLAC3, Antibody; PLAC3 Antibody; PLAC3; PAPPE; PAPP-E; PAPP-A2; Pappalysin-2; Pregnancy-associated plasma protein A2; pappalysin 2; anti-PAPPA2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
PLAC3 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1791
Applicable Applications for anti-PAPPA2 antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
PLAC3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human PLAC3.
Buffer
PLAC3 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
PLAC3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of PLAC3 in HeLa cells with PLAC3 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of PLAC3 in HeLa cells with PLAC3 antibody at 20 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of PLAC3 in HeLa cells with PLAC3 antibody at 10 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of PLAC3 in HeLa cells with PLAC3 antibody at 10 μg/mL.)
WB (Western Blot)
(Western blot analysis of PLAC3 in HeLa cell lysate with PLAC3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of PLAC3 in HeLa cell lysate with PLAC3 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-PAPPA2 antibody
PLAC3 Antibody: PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
92,136 Da
NCBI Official Full Name
pappalysin-2 isoform 1
NCBI Official Synonym Full Names
pappalysin 2
NCBI Official Symbol
PAPPA2
NCBI Official Synonym Symbols
PAPPE; PLAC3; PAPP-E; PAPP-A2
NCBI Protein Information
pappalysin-2; placenta-specific 3; pregnancy-associated plasma protein E1; pregnancy-associated plasma preproprotein-A2
UniProt Protein Name
Pappalysin-2
UniProt Gene Name
PAPPA2
UniProt Synonym Gene Names
PLAC3; PAPP-A2; PAPP-E
UniProt Entry Name
PAPP2_HUMAN
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Product Notes
The PAPPA2 pappa2 (Catalog #AAA39750) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLAC3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLAC3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PAPPA2 pappa2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLAC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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