WB (Western Blot)
(Detection of human Plakoglobin by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), HEK293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Plakoglobin antibody AAA212271 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Plakoglobin was also immunoprecipitated by rabbit anti-Plakoglobin antibody which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 seconds (B).)
Rabbit anti-Human Plakoglobin Polyclonal Antibody | anti-JUP antibody
Rabbit anti-Plakoglobin Antibody, Affinity Purified
Gene Names
JUP; DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12
Reactivity
Human
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
Plakoglobin, Antibody; Rabbit anti-Plakoglobin Antibody, Affinity Purified; DPIII; catenin (cadherin-associated protein), gamma 80kDa; PDGB; PKGB; junction plakoglobin; DP3; desmoplakin-3; desmoplakin III; Catenin gamma; CTNNG; Junction plakoglobin; anti-JUP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-JUP antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot)
Predicted Reactivity
Mouse
Immunogen
Between 695 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human Plakoglobin by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), HEK293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Plakoglobin antibody AAA212271 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Plakoglobin was also immunoprecipitated by rabbit anti-Plakoglobin antibody which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 seconds (B).)
WB (Western Blot)
(Detection of human Plakoglobin by western blot and immunoprecipitation. Samples: Whole cell lysate from HeLa (15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), HEK293T (T; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Plakoglobin antibody AAA212271 used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 6 ug/mg lysate. Plakoglobin was also immunoprecipitated by rabbit anti-Plakoglobin antibody which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 seconds (B).)
IHC (Immunohiostchemistry)
(Detection of human Plakoglobin by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Plakoglobin (Cat. No. AAA212271 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of human Plakoglobin by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-Plakoglobin (Cat. No. AAA212271 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human Plakoglobin by immunohistochemistry. Sample: FFPE section of human prostate hyperplasia. Antibody: Affinity purified rabbit anti-Plakoglobin (Cat. No. AAA212271 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human Plakoglobin by immunohistochemistry. Sample: FFPE section of human prostate hyperplasia. Antibody: Affinity purified rabbit anti-Plakoglobin (Cat. No. AAA212271 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
Related Product Information for anti-JUP antibody
Plakoglobin (gamma-catenin) is a member of the catenin family of proteins. It bears an armadillo repeat motif and plays a role in cell signaling; but unlike beta-catenenin, which plays a major role in the Wnt signaling pathway, plakoglobin is thought to act as a tumor/metastasis suppressor. Plakoglobin also functions as a junctional plaque protein and forms complexes with cadherins and desmosomal cadherins.
Product Categories/Family for anti-JUP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
81,745 Da
NCBI Official Full Name
junction plakoglobin
NCBI Official Synonym Full Names
junction plakoglobin
NCBI Official Symbol
JUP
NCBI Official Synonym Symbols
DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12
NCBI Protein Information
junction plakoglobin; desmoplakin-3; desmoplakin III; catenin (cadherin-associated protein), gamma 80kDa
UniProt Protein Name
Junction plakoglobin
UniProt Gene Name
JUP
UniProt Synonym Gene Names
CTNNG; DP3
UniProt Entry Name
PLAK_HUMAN
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Product Notes
The JUP jup (Catalog #AAA212271) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Plakoglobin Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Plakoglobin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the JUP jup for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Plakoglobin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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