WB (Western Blot)
(Western blot analysis of lysates from Hela, HepG2, K562, MCF-7 cell line (from left to right), using PMM2 Antibody (C-term). AAA285759 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Rabbit PMM2 Polyclonal Antibody | anti-PMM2 antibody
PMM2 Antibody (C-term)
Gene Names
PMM2; PMI; CDG1; CDGS; PMI1; CDG1a; PMM 2
Reactivity
Human (Predicted Reactivity: Bovine, Monkey, Mouse)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PMM2, Antibody; PMM2 Antibody (C-term); Phosphomannomutase 2; PMM 2; PMM2; anti-PMM2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Monkey, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PMM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human PMM2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
198-226
Sequence Length
246
Applicable Applications for anti-PMM2 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of lysates from Hela, HepG2, K562, MCF-7 cell line (from left to right), using PMM2 Antibody (C-term). AAA285759 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
WB (Western Blot)
(Western blot analysis of lysates from Hela, HepG2, K562, MCF-7 cell line (from left to right), using PMM2 Antibody (C-term). AAA285759 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
WB (Western Blot)
(Western blot analysis of lysates from Hela, HepG2, K562, MCF-7 cell line (from left to right), using PMM2 Antibody (C-term). AAA285759 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
WB (Western Blot)
(Western blot analysis of lysates from Hela, HepG2, K562, MCF-7 cell line (from left to right), using PMM2 Antibody (C-term). AAA285759 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Related Product Information for anti-PMM2 antibody
The protein encoded by this gene catalyzes the
isomerization of mannose 6-phosphate to mannose 1-phosphate, which
is a precursor to GDP-mannose necessary for the synthesis of
dolichol-P-oligosaccharides. Mutations in this gene have been shown
to cause defects in glycoprotein biosynthesis, which manifests as
carbohydrate-deficient glycoprotein syndrome type I. [provided by
RefSeq].
isomerization of mannose 6-phosphate to mannose 1-phosphate, which
is a precursor to GDP-mannose necessary for the synthesis of
dolichol-P-oligosaccharides. Mutations in this gene have been shown
to cause defects in glycoprotein biosynthesis, which manifests as
carbohydrate-deficient glycoprotein syndrome type I. [provided by
RefSeq].
Product Categories/Family for anti-PMM2 antibody
References
Vega, A.I., et al. Hum. Mutat. 30(5):795-803(2009)
Coman, D., et al. Am. J. Med. Genet. A 146(3):389-392(2008)
Vermeer, S., et al. J. Neurol. 254(10):1356-1358(2007)
Coman, D., et al. J Clin Neurosci 14(7):668-672(2007)
Schollen, E., et al. Mol. Genet. Metab. 90(4):408-413(2007)
Coman, D., et al. Am. J. Med. Genet. A 146(3):389-392(2008)
Vermeer, S., et al. J. Neurol. 254(10):1356-1358(2007)
Coman, D., et al. J Clin Neurosci 14(7):668-672(2007)
Schollen, E., et al. Mol. Genet. Metab. 90(4):408-413(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28082
NCBI Official Full Name
phosphomannomutase 2
NCBI Official Synonym Full Names
phosphomannomutase 2
NCBI Official Symbol
PMM2
NCBI Official Synonym Symbols
PMI; CDG1; CDGS; PMI1; CDG1a; PMM 2
NCBI Protein Information
phosphomannomutase 2
UniProt Protein Name
Phosphomannomutase 2
UniProt Gene Name
PMM2
UniProt Synonym Gene Names
PMM 2
UniProt Entry Name
PMM2_HUMAN
Similar Products
Product Notes
The PMM2 pmm2 (Catalog #AAA285759) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 198-226. The PMM2 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Monkey, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's PMM2 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PMM2 pmm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PMM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.