WB (Western Blot)
(PNPT1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the PNPT1 antibody detected the PNPT1 protein (arrow).)
Rabbit anti-Human, mouse PNPT1 Polyclonal Antibody | anti-PNPT1 antibody
PNPT1 Antibody (Center)
Gene Names
PNPT1; OLD35; DFNB70; PNPASE; old-35; COXPD13
Reactivity
Human, mouse
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PNPT1, Antibody; PNPT1 Antibody (Center); Polyribonucleotide nucleotidyltransferase 1; mitochondrial; 3'-5' RNA exonuclease OLD35; PNPase old-35; Polynucleotide phosphorylase 1; PNPase 1; Polynucleotide phosphorylase-like protein; PNPT1; PNPASE; anti-PNPT1 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PNPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 amino acids from the Central region of human PNPT1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
284-311
Sequence Length
783
Applicable Applications for anti-PNPT1 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(PNPT1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the PNPT1 antibody detected the PNPT1 protein (arrow).)
WB (Western Blot)
(PNPT1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the PNPT1 antibody detected the PNPT1 protein (arrow).)
WB (Western Blot)
(PNPT1 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PNPT1 antibody detected the PNPT1 protein (arrow).)
WB (Western Blot)
(PNPT1 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PNPT1 antibody detected the PNPT1 protein (arrow).)
Related Product Information for anti-PNPT1 antibody
PNPT1 is a subunit of the exosome complex, which is
involved in 3-prime-to-5-prime exoribonuclease activity for RNA
processing and degradation (Raijmakers et al., 2002 [PubMed
12419256]).
involved in 3-prime-to-5-prime exoribonuclease activity for RNA
processing and degradation (Raijmakers et al., 2002 [PubMed
12419256]).
Product Categories/Family for anti-PNPT1 antibody
References
Wang, G., et al. Cell 142(3):456-467(2010)
Das, S.K., et al. Proc. Natl. Acad. Sci. U.S.A. 107(26):11948-11953(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
O'Doherty, C., et al. Pharmacogenomics 10(7):1177-1186(2009)
Luczynski, W., et al. Neoplasma 56(5):428-434(2009)
Das, S.K., et al. Proc. Natl. Acad. Sci. U.S.A. 107(26):11948-11953(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
O'Doherty, C., et al. Pharmacogenomics 10(7):1177-1186(2009)
Luczynski, W., et al. Neoplasma 56(5):428-434(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
85951
NCBI Official Full Name
polyribonucleotide nucleotidyltransferase 1, mitochondrial
NCBI Official Synonym Full Names
polyribonucleotide nucleotidyltransferase 1
NCBI Official Symbol
PNPT1
NCBI Official Synonym Symbols
OLD35; DFNB70; PNPASE; old-35; COXPD13
NCBI Protein Information
polyribonucleotide nucleotidyltransferase 1, mitochondrial
UniProt Protein Name
Polyribonucleotide nucleotidyltransferase 1, mitochondrial
UniProt Gene Name
PNPT1
UniProt Synonym Gene Names
PNPASE; PNPase 1
UniProt Entry Name
PNPT1_HUMAN
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Product Notes
The PNPT1 pnpt1 (Catalog #AAA285769) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 284-311. The PNPT1 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PNPT1 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PNPT1 pnpt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PNPT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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