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IHC (Immunohistochemistry)
(Detection of human PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.)
Rabbit anti-Human, Mouse PPP4R3 Alpha Polyclonal Antibody | anti-PPP4R3Alpha antibody
Rabbit anti-PPP4R3 Alpha IHC Antibody, Affinity Purified
Gene Names
SMEK1; smk1; FLFL1; smk-1; PP4R3A; MSTP033; KIAA2010
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
PPP4R3 Alpha, Antibody; Rabbit anti-PPP4R3 Alpha IHC Antibody, Affinity Purified; SMEK homolog 1; serine/threonine-protein phosphatase 4 regulatory subunit 3A; smk-1; smk1; SMEK homolog 1, suppressor of mek1; FLFL1; PP4R3; PP4R3A; MSTP033; KIAA2010; SMEK1; Serine/threonine-protein phosphatase 4 regulatory subunit 3A; protein phosphatase 4 regulatory subunit 3A; anti-PPP4R3Alpha antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Concentration
250ug/ml (varies by lot)
Applicable Applications for anti-PPP4R3Alpha antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Predicted Reactivity
Orangutan, Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset, Crab-eating macaque, Northern white-cheeked gibbon
Immunogen
Between 783 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
IHC (Immunohistochemistry)
(Detection of human PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.)
IHC (Immunohistochemistry)
(Detection of human PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.)
IHC (Immunohistochemisry)
(Detection of human PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemisry)
(Detection of human PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of human stomach carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of mouse PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of mouse PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human PPP4R3 Alpha by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-PPP4R3 Alpha (Cat. No. AAA214040) used at a dilution of 1:250. Detection: DAB)
Related Product Information for anti-PPP4R3Alpha antibody
PPP4R3 is a binding partner of the PPP4C catalytic subunit of the PP4 serine/threonine protein phosphatase. PPP4C is structurally related to PP2AC but does not associate with the same regulatory subunits. PPP4C associates with either the PPP4R1 or PPP4R2 regulatory subunit. In addition to PPP4R1 and PPP4R2, PPP4R3 has also been identified as a regulator of PPP4C function. PP4R3 functions with PP4C in the control of recovery from DNA damage. PP4R3 may function by targeting PPP4 to sites of DNA damage via an interaction with Rad53 (CHK2). PP4R3 is the human homolog of the Dictylostelium SMEK (suppressor of MEK). SMEK has been shown to be involved in cell polarization and chemotaxis via an involvement in the MEK1/ERK1 signaling pathway. SMEK also functions by controlling PPP4C localization to nucleus.
Product Categories/Family for anti-PPP4R3Alpha antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
95,368 Da
NCBI Official Full Name
serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1
NCBI Official Synonym Full Names
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
NCBI Official Symbol
SMEK1
NCBI Official Synonym Symbols
smk1; FLFL1; smk-1; PP4R3A; MSTP033; KIAA2010
NCBI Protein Information
serine/threonine-protein phosphatase 4 regulatory subunit 3A
UniProt Protein Name
Serine/threonine-protein phosphatase 4 regulatory subunit 3A
UniProt Gene Name
SMEK1
UniProt Synonym Gene Names
KIAA2010; PP4R3A; PPP4R3A
UniProt Entry Name
P4R3A_HUMAN
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Product Notes
The PPP4R3Alpha smek1 (Catalog #AAA214040) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-PPP4R3 Alpha IHC Antibody, Affinity Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PPP4R3 Alpha can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PPP4R3Alpha smek1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP4R3 Alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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