Rabbit PRC1 Polyclonal Antibody | anti-PRC1 antibody

PRC1 Antibody

Cat. Num. AAA40182

• Gene Names: PRC1; ASE1
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: PRC1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: PRC1, Antibody; PRC1 Antibody; PRC1; ASE1; Protein regulator of cytokinesis 1; protein regulator of cytokinesis 1; anti-PRC1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
• Purity/Purification: PRC1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 620

• Applicable Applications for anti-PRC1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: PRC1 antibody was raised against a 19 amino acid synthetic peptide near the center of human PRC1.
• Buffer: PRC1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: PRC1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of PRC1 in mouse skeletal muscle tissue with PRC1 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of PRC1 in mouse skeletal muscle tissue with PRC1 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of PRC1 in human skeletal muscle tissue lysate with Prc1 antibody at (A) 0.5 μg/ml and (B) 1 μg/mL.)

Related Product Information for anti-PRC1 antibody

PRC1 Antibody: PRC1 (Protein Regulator of Cytokinesis 1) is a key regulator of cytokinesis and has been identified as a substrate for several cyclin-dependent kinases (CDKs). High levels of PRC1 expression occurs during S and G2/M and drops dramatically after mitosis exit and G1 entry. It is located in the nucleus during interphase and binds to the midzone of mitotic spindles during anaphase and is localized to the cell midbody during cytokinesis. Depletion of PRC1 has been shown to prevent cellular cleavage, but it has no effect on nuclear division, demonstrating the importance of PRC1 in mitosis.

NCBI and Uniprot Product Information

• NCBI GI #: 4506039
• NCBI GeneID: 9055
• NCBI Accession #: NP_003972
• NCBI GenBank Nucleotide #: NM_003981.3
• UniProt Accession #: O43663; Q9BSB6; A6NC44; B4DLR1; H9KV59
• Molecular Weight: 70,191 Da
• NCBI Official Full Name: protein regulator of cytokinesis 1 isoform 1
• NCBI Official Synonym Full Names: protein regulator of cytokinesis 1
• NCBI Official Symbol: PRC1
• NCBI Official Synonym Symbols: ASE1
• NCBI Protein Information: protein regulator of cytokinesis 1; PRC1; protein regulating cytokinesis 1; anaphase spindle elongation 1 homolog
• UniProt Protein Name: Protein regulator of cytokinesis 1
• UniProt Gene Name: PRC1
• UniProt Entry Name: PRC1_HUMAN