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IHC (Immunohistochemistry)
(Anti-Presenilin 2 antibody, AAA45130, IHC(P)IHC(P): Rat Kidney Tissue)
Rabbit Presenilin 2 Polyclonal Antibody | anti-PSEN2 antibody
Anti-Presenilin 2 antibody
Gene Names
PSEN2; AD4; PS2; AD3L; STM2; CMD1V
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Presenilin 2, Antibody; Anti-Presenilin 2 antibody; Presenilin-2(PS-2); presenilin 2(Alzheimer disease 4); AD3L antibody; AD3LP antibody; AD4 antibody; AD5 antibody; Alzheimer disease 4 antibody; CMD1V antibody; E5-1 antibody; OTTHUMP00000035671 antibody; OTTHUMP00000035672 antibody; OTTHUMP00000228286 antibody; OTTHUMP00000228288 antibody; Presenilin 2(Alzheimer disease 4) antibody; Presenilin 2 antibody; Presenilin-2 CTF subunit antibody; PS-2 antibody; PS2 antibody; Psen2 antibody; PSN2_HUMAN antibody; PSNL2 antibody; STM-2 antibody; STM2 antibody; anti-PSEN2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
448
Applicable Applications for anti-PSEN2 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Presenilin 2 (39-51aa EDGENTAQWRSQE), different from the related mouse and rat sequences by two amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemistry)
(Anti-Presenilin 2 antibody, AAA45130, IHC(P)IHC(P): Rat Kidney Tissue)
IHC (Immunohistochemistry)
(Anti-Presenilin 2 antibody, AAA45130, IHC(P)IHC(P): Rat Kidney Tissue)
IHC (Immunohistochemisry)
(Anti-Presenilin 2 antibody, AAA45130, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
IHC (Immunohistochemisry)
(Anti-Presenilin 2 antibody, AAA45130, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
IHC (Immunohiostchemistry)
(Anti-Presenilin 2 antibody, AAA45130, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Presenilin 2 antibody, AAA45130, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-Presenilin 2 antibody, AAA45130, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: MCF-7 Cell LysateLane 4: HELA Cell LysateLane 5: SMMC Cell LysateLane 6: CEM Cell Lysate)
WB (Western Blot)
(Anti-Presenilin 2 antibody, AAA45130, Western blottingLane 1: Rat Brain Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: MCF-7 Cell LysateLane 4: HELA Cell LysateLane 5: SMMC Cell LysateLane 6: CEM Cell Lysate)
Related Product Information for anti-PSEN2 antibody
Description: Rabbit IgG polyclonal antibody for Presenilin-2(PSEN2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.
Background: Presenilin-2 is a protein that in humans is encoded by the PSEN2 gene. Kovacs et al.(1996) demonstrated that the expression patterns of PS1 and PS2 in the brain are extremely similar to each other and that messages for both are primarily detectable in neuronal populations. Immunochemical analyses indicated that PS1 and PS2 are similar in size and localize to similar intracellular compartments(endoplasmic reticulum and Golgi complex). Li et al.(1997) demonstrated that wildtype PS1 and PS2 are localized to the nuclear membrane, its associated interphase kinetochores, and the centrosomes.In melanocytic cells PSEN2 gene expression may be regulated by MITF.
Background: Presenilin-2 is a protein that in humans is encoded by the PSEN2 gene. Kovacs et al.(1996) demonstrated that the expression patterns of PS1 and PS2 in the brain are extremely similar to each other and that messages for both are primarily detectable in neuronal populations. Immunochemical analyses indicated that PS1 and PS2 are similar in size and localize to similar intracellular compartments(endoplasmic reticulum and Golgi complex). Li et al.(1997) demonstrated that wildtype PS1 and PS2 are localized to the nuclear membrane, its associated interphase kinetochores, and the centrosomes.In melanocytic cells PSEN2 gene expression may be regulated by MITF.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
50,011 Da
NCBI Official Full Name
Presenilin-2
NCBI Official Synonym Full Names
presenilin 2
NCBI Official Symbol
PSEN2
NCBI Official Synonym Symbols
AD4; PS2; AD3L; STM2; CMD1V
NCBI Protein Information
presenilin-2; AD5; E5-1; PS-2; AD3LP; STM-2; Alzheimer disease 4
UniProt Protein Name
Presenilin-2
UniProt Gene Name
PSEN2
UniProt Synonym Gene Names
AD4; PS2; PSNL2; STM2; PS-2
UniProt Entry Name
PSN2_HUMAN
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Product Notes
The PSEN2 psen2 (Catalog #AAA45130) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Presenilin 2 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Presenilin 2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PSEN2 psen2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Presenilin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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