IHC (Immunohiostchemistry)
(Proenkephalin/PENK Antibody-Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.)
Rabbit Proenkephalin/PENK Polyclonal Antibody | anti-PENK antibody
Proenkephalin/PENK Rabbit anti-Human Polyclonal (aa 25-267) Antibody
Reactivity
Mouse, Rat, Human
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry
Purity
Affinity purified
Synonyms
Proenkephalin/PENK, Antibody; Proenkephalin/PENK Rabbit anti-Human Polyclonal (aa 25-267) Antibody; PathPlus Proenkephalin/PENK Antibody (aa 25-267); PENK; Enkephalin A; Met enkephalin; Preproenkephalin; Proenkephalin; Proenkephalin-A; anti-PENK antibody
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human Proenkephalin/PENK
Purity/Purification
Affinity purified
Form/Format
PBS, pH7.3, 0.02% Sodium Azide, 50% Glycerol
Concentration
2.08mg/ml (varies by lot)
Applicable Applications for anti-PENK antibody
WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Target
Human Proenkephalin/PENK
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 25-267 of human PENK (NP_001129162.1). ECSQDCATCSYRLVRPADINFLACVMECEGKLPSLKIWETCKELLQLSKPELPQDGTSTLRENSKPEESHLLAKRYGGFMKRYGGFMKKMDELYPMEPEEEANGSEILAKRYGGFMKKDAEEDDSLANSSDLLKELLETGDNRERSHHQDGSDNEEEVSKRYGGFMRGLKRSPQLEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAEALPSDEEGESYSKEVPEMEKRYGGFMRF
Conjugation
Unconjugated
Epitope
aa 25-267
Family
Endogenous opioids
Preparation and Storage
Store at -20 degree C. Avoid freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Proenkephalin/PENK Antibody-Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.)
IHC (Immunohiostchemistry)
(Proenkephalin/PENK Antibody-Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.)
WB (Western Blot)
(Proenkephalin/PENK Antibody-Western blot analysis of extracts of various cell lines.)
WB (Western Blot)
(Proenkephalin/PENK Antibody-Western blot analysis of extracts of various cell lines.)
Related Product Information for anti-PENK antibody
PENK antibody is an unconjugated rabbit polyclonal antibody to PENK (Proenkephalin)(aa 25-267) from human. It is reactive with human, mouse and rat. Validated for IHC and WB. Cited in 1 publication.
PENK (proenkephalin) is an endogenous opioid polypeptide hormone that produces multiple enkephalin peptides. Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.
PENK (proenkephalin) is an endogenous opioid polypeptide hormone that produces multiple enkephalin peptides. Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum.
References
The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,787 Da
NCBI Official Full Name
proenkephalin-A preproprotein
NCBI Official Synonym Full Names
proenkephalin
NCBI Official Symbol
PENK
NCBI Protein Information
proenkephalin-A; enkephalin A; preproenkephalin
UniProt Protein Name
Proenkephalin-A
UniProt Gene Name
PENK
UniProt Synonym Gene Names
OGF
UniProt Entry Name
PENK_HUMAN
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Product Notes
The PENK penk (Catalog #AAA162886) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Proenkephalin/PENK Rabbit anti-Human Polyclonal (aa 25-267) Antibody reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Proenkephalin/PENK can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PENK penk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Proenkephalin/PENK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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