IHC (Immunohistochemistry)
(Staining of Hep G2 cells with PCSK9 antibody at 2 ug/ml.)
Rabbit anti-Human Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE Polyclonal Antibody | anti-PCSK9 antibody
Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE
Gene Names
PCSK9; FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Immunoaffinity Purification.
Synonyms
Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE, Antibody; Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE; Proprotein convertase PC9; Subtilisin/kexin-like protease PC9; Neural apoptosis-regulated convertase 1; anti-PCSK9 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Immunoaffinity Purification.
Form/Format
Provided as solution in phosphate buffered saline with 0.08% sodium azide
Concentration
0.35mg/ml (varies by lot)
Sequence Length
692
Applicable Applications for anti-PCSK9 antibody
ELISA, WB (Western Blot)
Immunogen
Synthetic peptide derived from the human PCSK9 protein reported to block PCSK9-LDLR interaction.
Positive Control
Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells.
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
IHC (Immunohistochemistry)
(Staining of Hep G2 cells with PCSK9 antibody at 2 ug/ml.)
IHC (Immunohistochemistry)
(Staining of Hep G2 cells with PCSK9 antibody at 2 ug/ml.)
Related Product Information for anti-PCSK9 antibody
This anitbody is made to an epitope that is reported to block the PCSK9?LDLR (low density lipoprotein receptor) interaction. PCSK9 binds to the EGF-A domain of the LDLR and signals LDLR degradation. Reduced LDLR levels result in decreased LDL (low density lipid) metabolism leading to hypercholesterolemia.
Product Categories/Family for anti-PCSK9 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
73 kDa
NCBI Official Full Name
proprotein convertase subtilisin/kexin type 9 preproprotein
NCBI Official Synonym Full Names
proprotein convertase subtilisin/kexin type 9
NCBI Official Symbol
PCSK9
NCBI Official Synonym Symbols
FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3
NCBI Protein Information
proprotein convertase subtilisin/kexin type 9; subtilisin/kexin-like protease PC9; neural apoptosis regulated convertase 1; convertase subtilisin/kexin type 9 preproprotein
UniProt Protein Name
Proprotein convertase subtilisin/kexin type 9
UniProt Gene Name
PCSK9
UniProt Synonym Gene Names
NARC1; NARC-1; PC9
UniProt Entry Name
PCSK9_HUMAN
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Product Notes
The PCSK9 pcsk9 (Catalog #AAA60507) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PCSK9 pcsk9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Proprotein convertase subtilisin/kexin type 9 (PCSK9), NARC1 BLOCKING EPITOPE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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