Rabbit Prosapip2 Polyclonal Antibody | anti-TBKBP1 antibody

Prosapip2 Antibody

Cat. Num. AAA307152

• Gene Names: TBKBP1; SINTBAD; ProSAPiP2
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Affinity chromatography purified via peptide column
• Synonyms: Prosapip2, Antibody; Prosapip2 Antibody; TANK-binding kinase 1-binding protein, TBK1-binding protein 1, TBKBP1, SINTBAD; anti-TBKBP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Purity/Purification: Affinity chromatography purified via peptide column
• Form/Format: Supplied in PBS containing 0.02% sodium azide.
• Sequence Length: 615

• Applicable Applications for anti-TBKBP1 antibody: IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Immunogen Type: Peptide
• Immunogen Description: Raised against a 16 amino acid peptide from near the carboxy terminus of human Prosapip2.
• Target Name: Prosapip2
• Preparation and Storage: Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IHC (Immunohiostchemistry)

(Immunohistochemistry of Prosapip2 in rat liver tissue with Prosapip2 antibody at 5 ug/mL.)

WB (Western Blot)

(Western blot analysis of Prosapip2 in rat liver tissue lysate with Prosapip2 antibody at 1 ug/mL.)

Related Product Information for anti-TBKBP1 antibody

Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kB pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.

Product Categories/Family for anti-TBKBP1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 7662302
• NCBI GeneID: 9755
• NCBI Accession #: NP_055541
• NCBI GenBank Nucleotide #: NM_014726.2
• Molecular Weight: 25,043 Da
• NCBI Official Full Name: TANK-binding kinase 1-binding protein 1
• NCBI Official Synonym Full Names: TBK1 binding protein 1
• NCBI Official Symbol: TBKBP1
• NCBI Official Synonym Symbols: SINTBAD; ProSAPiP2
• NCBI Protein Information: TANK-binding kinase 1-binding protein 1
• UniProt Protein Name: TANK-binding kinase 1-binding protein 1
• UniProt Gene Name: TBKBP1
• UniProt Synonym Gene Names: TBK1-binding protein 1
• UniProt Entry Name: TBKB1_HUMAN