Rabbit protein tyrosine phosphatase, non-receptor type 1 Polyclonal Antibody | anti-PTPN1 antibody
Rabbit anti-human protein tyrosine phosphatase, non-receptor type 1 polyclonal Antibody
Gene Names
PTPN1; PTP1B
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
protein tyrosine phosphatase, non-receptor type 1, Antibody; Rabbit anti-human protein tyrosine phosphatase, non-receptor type 1 polyclonal Antibody; protein tyrosine phosphatase; non-receptor type 1; PTPN1; PTP1B; anti-PTPN1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Sequence Length
435
Applicable Applications for anti-PTPN1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Human PTPN1
Product Type
Purified Rabbit Anti human PolyClonal Antibody
Immunogen Species
Homo sapiens (Human)
Target Names
PTPN1
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1719 / sc-1718 / sc-14021
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Related Product Information for anti-PTPN1 antibody
This protein is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Protein tyrosine phosphatase, non-receptor type 1
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 1
NCBI Official Symbol
PTPN1
NCBI Official Synonym Symbols
PTP1B
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 1; protein-tyrosine phosphatase 1B; protein tyrosine phosphatase, placental
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 1
UniProt Gene Name
PTPN1
UniProt Synonym Gene Names
PTP1B; PTP-1B
UniProt Entry Name
PTN1_HUMAN
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Product Notes
The PTPN1 ptpn1 (Catalog #AAA81083) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human protein tyrosine phosphatase, non-receptor type 1 polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's protein tyrosine phosphatase, non-receptor type 1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PTPN1 ptpn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "protein tyrosine phosphatase, non-receptor type 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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