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WB (Western Blot)
(Anti-PSD95 antibody, AAA45684, All Western blottingAll lanes: Anti-DLG4 (AAA45684) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 80KDObserved bind size: 100KD)
Rabbit PSD95 Polyclonal Antibody | anti-DLG4 antibody
Anti-PSD95 antibody
Gene Names
DLG4; PSD95; SAP90; SAP-90
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
PSD95, Antibody; Anti-PSD95 antibody; Disks large homolog 4; discs, large homolog 4(Drosophila); Discs large homolog 4 antibody; Disks large homolog 4 antibody; DLG 4 antibody; DLG4 antibody; DLG4_HUMAN antibody; FLJ97752 antibody; FLJ98574 antibody; Human post synaptic density protein 95 antibody; Human post-synaptic density protein 95 antibody; Post synaptic density protein 95 antibody; Postsynaptic density protein 95 antibody; PSD 95 antibody; PSD-95 antibody; PSD95 antibody; SAP 90 antibody; SAP-90 antibody; SAP90 antibody; Synapse associated protein 90 antibody; Synapse-associated protein 90 antibody; Tax interaction protein 15 antibody; anti-DLG4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
724
Applicable Applications for anti-DLG4 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human PSD95 (492-507aa RRVERREWSRLKAKDW), identical to the related rat and mouse sequences.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti-PSD95 antibody, AAA45684, All Western blottingAll lanes: Anti-DLG4 (AAA45684) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 80KDObserved bind size: 100KD)
WB (Western Blot)
(Anti-PSD95 antibody, AAA45684, All Western blottingAll lanes: Anti-DLG4 (AAA45684) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 40ugLane 2: HELA Whole Cell Lysate at 40ugPredicted bind size: 80KDObserved bind size: 100KD)
IHC (Immunohistochemisry)
(Anti-PSD95 antibody, AAA45684, IHC(P)IHC(P): Human Placenta Tissue)
IHC (Immunohistochemisry)
(Anti-PSD95 antibody, AAA45684, IHC(P)IHC(P): Human Placenta Tissue)
IHC (Immunohiostchemistry)
(Anti-PSD95 antibody, AAA45684, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-PSD95 antibody, AAA45684, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-PSD95 antibody, AAA45684, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-PSD95 antibody, AAA45684, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
Related Product Information for anti-DLG4 antibody
Description: Rabbit IgG polyclonal antibody for Disks large homolog 4(DLG4) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: DLG4 discs large homolog 4, also known as PSD95 or SAP-90, is a protein that in humans is encoded by the DLG4 gene. It is a member of the membrane-associated guanylate kinase(MAGUK) family. This gene is mapped to 17p13.1. DLG4 can heteromultimerize with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Overexpression of DLG4 in hippocampal neurons could drive maturation of glutamatergic synapses. DLG4 can orchestrate synaptic development and it has a role in synapse stabilization and plasticity. Ubiquitination of DLG4 through an MDM2-mediated pathway can regulate AMPA receptor surface expression during synaptic plasticity.
Background: DLG4 discs large homolog 4, also known as PSD95 or SAP-90, is a protein that in humans is encoded by the DLG4 gene. It is a member of the membrane-associated guanylate kinase(MAGUK) family. This gene is mapped to 17p13.1. DLG4 can heteromultimerize with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Overexpression of DLG4 in hippocampal neurons could drive maturation of glutamatergic synapses. DLG4 can orchestrate synaptic development and it has a role in synapse stabilization and plasticity. Ubiquitination of DLG4 through an MDM2-mediated pathway can regulate AMPA receptor surface expression during synaptic plasticity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
80,125 Da
NCBI Official Full Name
Disks large homolog 4
NCBI Official Synonym Full Names
discs, large homolog 4 (Drosophila)
NCBI Official Symbol
DLG4
NCBI Official Synonym Symbols
PSD95; SAP90; SAP-90
NCBI Protein Information
disks large homolog 4; discs large homolog 4; Tax interaction protein 15; synapse-associated protein 90; postsynaptic density protein 95; post-synaptic density protein 95
UniProt Protein Name
Disks large homolog 4
UniProt Gene Name
DLG4
UniProt Synonym Gene Names
PSD95; PSD-95; SAP-90; SAP90
UniProt Entry Name
DLG4_HUMAN
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Product Notes
The DLG4 dlg4 (Catalog #AAA45684) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PSD95 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PSD95 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the DLG4 dlg4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSD95, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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