IHC (Immunohistochemisry)
(PSMB5 Antibody (C-term) (AAA289700)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PSMB5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human PSMB5 Polyclonal Antibody | anti-PSMB5 antibody
PSMB5 Antibody (C-term)
Gene Names
PSMB5; X; MB1; LMPX
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PSMB5, Antibody; PSMB5 Antibody (C-term); Proteasome subunit beta type-5; Macropain epsilon chain; Multicatalytic endopeptidase complex epsilon chain; Proteasome chain 6; Proteasome epsilon chain; Proteasome subunit MB1; Proteasome subunit X; PSMB5; LMPX; MB1; X; anti-PSMB5 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PSMB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the C-terminal region of human PSMB5.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
235-263
Sequence Length
160
Applicable Applications for anti-PSMB5 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(PSMB5 Antibody (C-term) (AAA289700)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PSMB5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(PSMB5 Antibody (C-term) (AAA289700)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PSMB5 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of PSMB5 (arrow) using rabbit polyclonal PSMB5 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PSMB5 gene.)
WB (Western Blot)
(Western blot analysis of PSMB5 (arrow) using rabbit polyclonal PSMB5 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PSMB5 gene.)
WB (Western Blot)
(PSMB5 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PSMB5 antibody detected the PSMB5 protein (arrow).)
WB (Western Blot)
(PSMB5 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PSMB5 antibody detected the PSMB5 protein (arrow).)
Related Product Information for anti-PSMB5 antibody
The proteasome is a multicatalytic proteinase complex with
a highly ordered ring-shaped 20S core structure. The core structure
is composed of 4 rings of 28 non-identical subunits; 2 rings are
composed of 7 alpha subunits and 2 rings are composed of 7 beta
subunits. Proteasomes are distributed throughout eukaryotic cells
at a high concentration and cleave peptides in an
ATP/ubiquitin-dependent process in a non-lysosomal pathway. An
essential function of a modified proteasome, the immunoproteasome,
is the processing of class I MHC peptides. This gene encodes a
member of the proteasome B-type family, also known as the T1B
family, that is a 20S core beta subunit in the proteasome. This
catalytic subunit is not present in the immunoproteasome and is
replaced by catalytic subunit 3i (proteasome beta 8 subunit).
Multiple transcript variants encoding different isoforms have been
found for this gene.
a highly ordered ring-shaped 20S core structure. The core structure
is composed of 4 rings of 28 non-identical subunits; 2 rings are
composed of 7 alpha subunits and 2 rings are composed of 7 beta
subunits. Proteasomes are distributed throughout eukaryotic cells
at a high concentration and cleave peptides in an
ATP/ubiquitin-dependent process in a non-lysosomal pathway. An
essential function of a modified proteasome, the immunoproteasome,
is the processing of class I MHC peptides. This gene encodes a
member of the proteasome B-type family, also known as the T1B
family, that is a 20S core beta subunit in the proteasome. This
catalytic subunit is not present in the immunoproteasome and is
replaced by catalytic subunit 3i (proteasome beta 8 subunit).
Multiple transcript variants encoding different isoforms have been
found for this gene.
Product Categories/Family for anti-PSMB5 antibody
References
Ri, M., et al. Leukemia 24(8):1506-1512(2010)
Lu, S., et al. Exp. Hematol. 37(7):831-837(2009)
Lu, S., et al. Exp. Hematol. 36(10):1278-1284(2008)
Oerlemans, R., et al. Blood 112(6):2489-2499(2008)
Wang, L., et al. Clin. Cancer Res. 14(11):3503-3513(2008)
Lu, S., et al. Exp. Hematol. 37(7):831-837(2009)
Lu, S., et al. Exp. Hematol. 36(10):1278-1284(2008)
Oerlemans, R., et al. Blood 112(6):2489-2499(2008)
Wang, L., et al. Clin. Cancer Res. 14(11):3503-3513(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28480
NCBI Official Full Name
proteasome subunit beta type-5 isoform 2
NCBI Official Synonym Full Names
proteasome (prosome, macropain) subunit, beta type, 5
NCBI Official Symbol
PSMB5
NCBI Official Synonym Symbols
X; MB1; LMPX
NCBI Protein Information
proteasome subunit beta type-5
UniProt Protein Name
Proteasome subunit beta type-5
UniProt Gene Name
PSMB5
UniProt Synonym Gene Names
LMPX; MB1; X
UniProt Entry Name
PSB5_HUMAN
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Product Notes
The PSMB5 psmb5 (Catalog #AAA289700) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 235-263. The PSMB5 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PSMB5 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PSMB5 psmb5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSMB5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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