IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human tonsil tissue using AAA232003 at dilution 1:100)
Rabbit anti-Human, Mouse PSTPIP1 Polyclonal Antibody | anti-PSTPIP1 antibody
PSTPIP1 Antibody
Gene Names
PSTPIP1; H-PIP; PAPAS; CD2BP1; PSTPIP; CD2BP1L; CD2BP1S
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
PSTPIP1, Antibody; PSTPIP1 Antibody; Proline-serine-threonine phosphatase-interacting protein 1; PEST phosphatase-interacting protein 1; CD2-binding protein 1; H-PIP; PSTPIP1; CD2BP1; anti-PSTPIP1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid; PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Sequence Length
397
Applicable Applications for anti-PSTPIP1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant Human Proline-serine-threonine phosphatase-interacting protein 1 protein (157-416AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Research Area
Signal Transduction
Target Names
PSTPIP1
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-104630 / sc-104631
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human tonsil tissue using AAA232003 at dilution 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human tonsil tissue using AAA232003 at dilution 1:100)
WB (Western Blot)
(Western blotAll lanes: PSTPIP1 antibody at 0.85 ug/mlLane 1: Mouse brain tissueLane 2: Raw264.7 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 48,46 kDaObserved band size: 48 kDa)
WB (Western Blot)
(Western blotAll lanes: PSTPIP1 antibody at 0.85 ug/mlLane 1: Mouse brain tissueLane 2: Raw264.7 whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 48,46 kDaObserved band size: 48 kDa)
Related Product Information for anti-PSTPIP1 antibody
Involved in regulation of the actin cytoskeleton. May regulate WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS and allow PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation (By similarity). Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2. Also has a role in innate immunity and the inflammatory response. Recruited to inflammasomes by MEFV. Induces formation of pyroptosomes, large supramolecular structures composed of oligomerized PYCARD dimers which form prior to inflammatory apoptosis. Binding to MEFV allows MEFV to bind to PYCARD and facilitates pyroptosome formation. Regulates endocytosis and cell migration in neutrophils.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
proline-serine-threonine phosphatase-interacting protein 1 isoform 2
NCBI Official Synonym Full Names
proline-serine-threonine phosphatase interacting protein 1
NCBI Official Symbol
PSTPIP1
NCBI Official Synonym Symbols
H-PIP; PAPAS; CD2BP1; PSTPIP; CD2BP1L; CD2BP1S
NCBI Protein Information
proline-serine-threonine phosphatase-interacting protein 1
UniProt Protein Name
Proline-serine-threonine phosphatase-interacting protein 1
UniProt Gene Name
PSTPIP1
UniProt Synonym Gene Names
CD2BP1; PEST phosphatase-interacting protein 1
UniProt Entry Name
PPIP1_HUMAN
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Product Notes
The PSTPIP1 pstpip1 (Catalog #AAA232003) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PSTPIP1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PSTPIP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PSTPIP1 pstpip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PSTPIP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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