IHC (Immunohiostchemistry)
(Anti-PTHR / PTHR1 antibody IHC of human Bone, Giant Cell Tumor. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit PTHR / PTHR1 Polyclonal Antibody | anti-PTHR antibody
Rabbit Polyclonal to Human PTHR / PTHR1
Gene Names
PTH1R; PFE; PTHR; PTHR1
Reactivity
Human, MonkeyPredicted Reactivity: Gorilla, Orangutan, Gibbon, Bovine, Dog, Pig (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
PTHR / PTHR1, Antibody; Rabbit Polyclonal to Human PTHR / PTHR1; Anti-PTHR / PTHR1 Antibody (N-Terminus) IHC-plus; PTH1R; Parathyroid hormone 1 receptor; Parathyroid hormone receptor 1; PFE; Pth-related peptide receptor; PTHR; PTH/PTHr receptor; Pth/pthrp receptor; Parathyroid hormone receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTHR1; PTHrP-R; PTHrP-receptor; Human PTHR; anti-PTHR antibody
Host
Rabbit
Reactivity
Human, Monkey
Predicted Reactivity: Gorilla, Orangutan, Gibbon, Bovine, Dog, Pig (at least 90% immunogen sequence identity)
Predicted Reactivity: Gorilla, Orangutan, Gibbon, Bovine, Dog, Pig (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human PTH1R. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except UHRF1BP1 (40%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
593
Applicable Applications for anti-PTHR antibody
IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic 20 amino acid peptide from N-terminal extracellular domain of human PTH1R. Percent identity with other species by BLAST analysis: Human, Monkey, Marmoset (100%); Gorilla, Gibbon, Bovine, Pig (95%); Orangutan, Elephant, Dog (90%).
Immunogen Type
Synthetic peptide
Immunogen
PTHR / PTHR1 antibody was raised against synthetic 20 amino acid peptide from N-terminal extracellular domain of human PTH1R. Percent identity with other species by BLAST analysis: Human, Monkey, Marmoset (100%); Gorilla, Gibbon, Bovine, Pig (95%); Orangutan, Elephant, Dog (90%); Panda, Horse (85%); Rabbit (80%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
IHC (Immunohiostchemistry)
(Anti-PTHR / PTHR1 antibody IHC of human Bone, Giant Cell Tumor. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-PTHR / PTHR1 antibody IHC of human Bone, Giant Cell Tumor. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-PTH1R antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-PTH1R antibody IHC of human kidney, renal tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-PTHR antibody
PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR.
Product Categories/Family for anti-PTHR antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66,361 Da
NCBI Official Full Name
parathyroid hormone/parathyroid hormone-related peptide receptor
NCBI Official Synonym Full Names
parathyroid hormone 1 receptor
NCBI Official Symbol
PTH1R
NCBI Official Synonym Symbols
PFE; PTHR; PTHR1
NCBI Protein Information
parathyroid hormone/parathyroid hormone-related peptide receptor; PTH1 receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; parathyroid hormone receptor 1; seven transmembrane helix receptor; parathyroid hormone/parathyroid hormone-related protein receptor
UniProt Protein Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
UniProt Gene Name
PTH1R
UniProt Synonym Gene Names
PTHR; PTHR1; PTH/PTHr receptor; PTH1 receptor
UniProt Entry Name
PTH1R_HUMAN
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Product Notes
The PTHR pth1r (Catalog #AAA51340) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human PTHR / PTHR1 reacts with Human, Monkey Predicted Reactivity: Gorilla, Orangutan, Gibbon, Bovine, Dog, Pig (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's PTHR / PTHR1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PTHR pth1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTHR / PTHR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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