Rabbit PTK6 Polyclonal Antibody | anti-PTK6 antibody

Rabbit Anti PTK6

Cat. Num. AAA50321

• Gene Names: PTK6; BRK
• Reactivity: Human, Rat, Mouse
• Applications: Western Blot
• Purity: Purified IgG was prepared from whole serum by affinity chromatography.
• Synonyms: PTK6, Antibody; Rabbit Anti PTK6; PTK6 antibody; anti-PTK6 antibody

• Host: Rabbit
• Reactivity: Human, Rat, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified IgG was prepared from whole serum by affinity chromatography.
• Form/Format: Liquid; Phosphate Buffered Saline
• Sequence Length: 134

• Applicable Applications for anti-PTK6 antibody: WB (Western Blot)
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 222-451 of human PTK6.
• Preservative Stabilizers: 0.02% Sodium Azide 50% Glycerol
• Preparation and Storage: Store at -20 degree C.; Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody.; Should this product contain a precipitate we recommend microcentrifugation before use.

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human gastric cancer tissue using Rabbit anti PTK6 antibody at a 1/100 dilution)

WB (Western Blot)

(Western blot analysis of various cell and tissue lysates using Rabbit anti PTK6 antibody at a 1/1000 dilution. 3% non-fat dry milk was used for blocking)

Related Product Information for anti-PTK6 antibody

Rabbit anti PTK6 antibody recognizes protein-tyrosine kinase 6, also known as breast tumor kinase and tyrosine-protein kinase BRK. PTK6 is a nonreceptor tyrosine kinase that is evolutionarily related to the FRK family of kinases and more distantly to the SRC family of tyrosine kinases (Qui and Miller 2002, Brauer and Tyner 2010). It controls various signaling pathways involved in the differentiation and maintenance of normal epithelia (Brauer and Tyner 2010). PTK6 substrates include AKT (Zhang et al. 2005), SLM1 and SLM2 (Haegebarth et al. 2004), STAT3 (Liu et al. 2006), STAT5b (Weaver and Silva 2007). PTK6 is coamplified and coexpressed with ErbB2 in human breast cancers to promote proliferation (Xiang et al. 2008).

NCBI and Uniprot Product Information

• NCBI GI #: 373432692
• NCBI GeneID: 5753
• NCBI Accession #: NP_001243287.1
• NCBI GenBank Nucleotide #: NM_001256358.1
• UniProt Accession #: Q13882
• NCBI Official Full Name: protein-tyrosine kinase 6 isoform 2
• NCBI Official Synonym Full Names: protein tyrosine kinase 6
• NCBI Official Symbol: PTK6
• NCBI Official Synonym Symbols: BRK
• NCBI Protein Information: protein-tyrosine kinase 6
• UniProt Protein Name: Protein-tyrosine kinase 6
• UniProt Gene Name: PTK6
• UniProt Synonym Gene Names: BRK
• UniProt Entry Name: PTK6_HUMAN