IHC (Immunohiostchemistry)
(PTPLA Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPLA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human PTPLA Polyclonal Antibody | anti-PTPLA antibody
PTPLA Antibody (N-term)
Gene Names
HACD1; CAP; PTPLA
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PTPLA, Antibody; PTPLA Antibody (N-term); Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1; 3-hydroxyacyl-CoA dehydratase 1; HACD1; Cementum attachment protein; Protein-tyrosine phosphatase-like member A; PTPLA; anti-PTPLA antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PTPLA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human PTPLA.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.41 (varies by lot)
Sequence Positions
37-66
Sequence Length
288
Applicable Applications for anti-PTPLA antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(PTPLA Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPLA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(PTPLA Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPLA Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(PTPLA Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPLA antibody detected the PTPLA protein (arrow).)
WB (Western Blot)
(PTPLA Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PTPLA antibody detected the PTPLA protein (arrow).)
Related Product Information for anti-PTPLA antibody
The protein encoded by this gene contains a characteristic
catalytic motif of the protein tyrosine phosphatases (PTPs) family.
The PTP motif of this protein has the highly conserved arginine
residue replaced by a proline residue; thus it may represent a
distinct class of PTPs. Members of the PTP family are known to be
signaling molecules that regulate a variety of cellular processes.
This gene was preferentially expressed in both adult and fetal
heart. A much lower expression level was detected in skeletal and
smooth muscle tissues, and no expression was observed in other
tissues. The tissue specific expression in the developing and adult
heart suggests a role in regulating cardiac development and
differentiation.
catalytic motif of the protein tyrosine phosphatases (PTPs) family.
The PTP motif of this protein has the highly conserved arginine
residue replaced by a proline residue; thus it may represent a
distinct class of PTPs. Members of the PTP family are known to be
signaling molecules that regulate a variety of cellular processes.
This gene was preferentially expressed in both adult and fetal
heart. A much lower expression level was detected in skeletal and
smooth muscle tissues, and no expression was observed in other
tissues. The tissue specific expression in the developing and adult
heart suggests a role in regulating cardiac development and
differentiation.
Product Categories/Family for anti-PTPLA antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Liang, X., et al. Hum. Mutat. 30(3):463-471(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Liang, X., et al. Hum. Mutat. 30(3):463-471(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32388
NCBI Official Full Name
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
NCBI Official Synonym Full Names
3-hydroxyacyl-CoA dehydratase 1
NCBI Official Symbol
HACD1
NCBI Official Synonym Symbols
CAP; PTPLA
NCBI Protein Information
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
UniProt Protein Name
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1
UniProt Gene Name
HACD1
UniProt Synonym Gene Names
CAP
UniProt Entry Name
HACD1_HUMAN
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Product Notes
The PTPLA hacd1 (Catalog #AAA288635) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 37-66. The PTPLA Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTPLA can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PTPLA hacd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPLA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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