IHC (Immunohistochemisry)
(Fig: 3 Immunocytochemical analysis of FAP-1 in cell lines using at 1: 2000. In ovarian carcinoma cell lines FAP-1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human 293 kidney and Jurkat T cell lines were used as positive and negative controls, respectively. The staining data correlates with the western blot data (figure to the left).)
Rabbit anti-Human PTPN13/PTPL1 Polyclonal Antibody | anti-PTPN13 antibody
Polyclonal Antibody to PTPN13/PTPL1 (FAP1)
Gene Names
PTPN13; PNP1; FAP-1; PTP1E; PTPL1; PTPLE; PTP-BL; hPTP1E; PTP-BAS
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunoprecipitation
Purity
Serum
Synonyms
PTPN13/PTPL1, Antibody; Polyclonal Antibody to PTPN13/PTPL1 (FAP1); PTPN13; PNP1; PTP1E; PTPL1; Fas-associated protein-tyrosine phosphatase 1; PTP-BAS; PTP-E1; Protein-tyrosine phosphatase 1E; Protein-tyrosine phosphatase PTPL1; Antibody to PTPN13/PTPL1 (FAP1); Anti-PTPN13/PTPL1 (FAP1) Antibody; PTPN13/PTPL1 (FAP1) Antibody; anti-PTPN13 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Serum
Form/Format
50 ul sera
Sequence Length
2485
Applicable Applications for anti-PTPN13 antibody
WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation)
Immunogen Information
A recombinant protein of human FAP-1 (amino acids 1279 to 1883) was used as immunogen for this antibody
Antigen
PTPN13/PTPL1 (FAP1)
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
IHC (Immunohistochemisry)
(Fig: 3 Immunocytochemical analysis of FAP-1 in cell lines using at 1: 2000. In ovarian carcinoma cell lines FAP-1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human 293 kidney and Jurkat T cell lines were used as positive and negative controls, respectively. The staining data correlates with the western blot data (figure to the left).)
IHC (Immunohistochemisry)
(Fig: 3 Immunocytochemical analysis of FAP-1 in cell lines using at 1: 2000. In ovarian carcinoma cell lines FAP-1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human 293 kidney and Jurkat T cell lines were used as positive and negative controls, respectively. The staining data correlates with the western blot data (figure to the left).)
IHC (Immunohiostchemistry)
(Fig: 2 Immunohistochemisty of FAP-1 in formalin-fixed, paraffin embedded ovarian carcinoma cores from a tissue microarray using at 1: 2000. A-D, samples are from four different patients. A1-D1 are high magnification images from A-D, respectively. Hematoxylin-eosin counterstain.)
IHC (Immunohiostchemistry)
(Fig: 2 Immunohistochemisty of FAP-1 in formalin-fixed, paraffin embedded ovarian carcinoma cores from a tissue microarray using at 1: 2000. A-D, samples are from four different patients. A1-D1 are high magnification images from A-D, respectively. Hematoxylin-eosin counterstain.)
WB (Western Blot)
(Fig: 1 Western blot analysis of FAP-1 using at 1: 2000. In ovarian carcinoma cell lines FAP-1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human Jurkat T and 293 kidney cell lines were used as negative and positive controls, respectively.)
WB (Western Blot)
(Fig: 1 Western blot analysis of FAP-1 using at 1: 2000. In ovarian carcinoma cell lines FAP-1 expression was detected in SK-OV-3 and OVCAR-3, but not in BG-1 or HEY. Human Jurkat T and 293 kidney cell lines were used as negative and positive controls, respectively.)
Related Product Information for anti-PTPN13 antibody
This antibody recognizes FAP-1, including FAP-1 isoforms; FAP-1 (also known as Fas-associated phosphatase-1, PTPN13, PTP-BAS, hPTPIE, and PTPL1) is a member of the protein tyrosine phosphatase (PTP) family. FAP-1 phosphatase is thought to be important in the Fas signaling pathway. FAP-1 binds to the cytosolic tail of the Fas receptor (Apo1, CD95) and inhibits Fas-induced apoptosis. Increased FAP-1 protein levels in some tumor cell lines and tumor tissues correlates with resistance to Fas-mediated apoptosis. In general, FAP-1 expression has been found to be highest in cell lines and tissues that are relatively resistant to Fas-mediated apoptosis. Gene transfer-mediated elevations in FAP-1 partially abolished Fas-induced apoptosis in a T cell line which is consistent with an inhibitory effect of FAP-1 on Fas signal transductions. Additionally, FAP-1 expression correlates with Fas resistant in ovarian cancer cell lines and FAP-1 is commonly expression in ovarian cancers.
Product Categories/Family for anti-PTPN13 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
277,508 Da
NCBI Official Full Name
Tyrosine-protein phosphatase non-receptor type 13
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 13
NCBI Official Symbol
PTPN13
NCBI Official Synonym Symbols
PNP1; FAP-1; PTP1E; PTPL1; PTPLE; PTP-BL; hPTP1E; PTP-BAS
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 13
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 13
UniProt Gene Name
PTPN13
UniProt Synonym Gene Names
PNP1; PTP1E; PTPL1; FAP-1; PTP-E1; hPTPE1
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Product Notes
The PTPN13 ptpn13 (Catalog #AAA78354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to PTPN13/PTPL1 (FAP1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTPN13/PTPL1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the PTPN13 ptpn13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPN13/PTPL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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