Rabbit PTPRE / PTP Epsilon Polyclonal Antibody | anti-PTPRE antibody

Rabbit Polyclonal to Human PTPRE / PTP Epsilon

Cat. Num. AAA51067

• Gene Names: PTPRE; PTPE; HPTPE; R-PTP-EPSILON
• Reactivity: Human; Predicted Reactivity: Monkey, Mouse, Bovine, Dog, Hamster, Horse (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: PTPRE / PTP Epsilon, Antibody; Rabbit Polyclonal to Human PTPRE / PTP Epsilon; Anti-PTPRE / PTP Epsilon Antibody (Cytoplasmic Domain) IHC-plus; PTPRE; HPTPE; PTPE; Ptpepsilon; R-PTP-EPSILON; PTPvarepsilon; PTP epsilon; Human PTPRE; PTP Epsilon; anti-PTPRE antibody

• Host: Rabbit
• Reactivity: Human; Predicted Reactivity: Monkey, Mouse, Bovine, Dog, Hamster, Horse (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human PTPRE. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except AMT (50%).
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 700

• Applicable Applications for anti-PTPRE antibody: IHC (Immunohistochemistry)
• Target Species: Human
• Immunogen Description: Synthetic 20 amino acid peptide from cytoplasmic domain of human PTPRE. Percent identity with other species by BLAST analysis: Human (100%); Marmoset (95%); Mouse, Hamster, Panda, Bovine, Dog, Horse (90%); Rat, Xenopus (85%).
• Immunogen Type: Synthetic peptide
• Immunogen: PTPRE / PTP Epsilon antibody was raised against synthetic 20 amino acid peptide from cytoplasmic domain of human PTPRE. Percent identity with other species by BLAST analysis: Human (100%); Marmoset (95%); Mouse, Hamster, Panda, Bovine, Dog, Horse (90%); Rat, Xenopus (85%); Elephant, Turkey, Chicken (80%).
• Antigen Modification: Cytoplasmic Domain
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

IHC (Immunohiostchemistry)

(Anti-PTPRE / PTP Epsilon antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

IHC (Immunohistochemistry)

(Anti-PTPRE antibody IHC of human colon, submucosal vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-PTPRE antibody

PTP epsilon, an R4 receptor protein tyrosine phosphatase, is composed of a short extracellular and two cytoplasmic protein phosphatase domains and has been shown to affect neuronal differentiation, endothelial cell growth, vascular development, and possibly mammary tumor development. It has been shown that the cytosolic form of PTP epsilon can be induced by IL-1 and TNF alpha in humans and is a negative regulator of IL-6- and LIF-induced Jak-STAT kinase signaling in rats.

Product Categories/Family for anti-PTPRE antibody

Family: Protein Phosphatase; Subfamily: R4

NCBI and Uniprot Product Information

• NCBI GI #: 5729993
• NCBI GeneID: 5791
• NCBI Accession #: NP_006495.1
• NCBI GenBank Nucleotide #: NM_006504.4
• UniProt Accession #: P23469; Q13345; Q5VWH3; Q5VWH4; Q96KQ6
• Molecular Weight: 71,382 Da
• NCBI Official Full Name: receptor-type tyrosine-protein phosphatase epsilon isoform 1
• NCBI Official Synonym Full Names: protein tyrosine phosphatase, receptor type, E
• NCBI Official Symbol: PTPRE
• NCBI Official Synonym Symbols: PTPE; HPTPE; R-PTP-EPSILON
• NCBI Protein Information: receptor-type tyrosine-protein phosphatase epsilon; protein tyrosine phosphatase, receptor type, epsilon polypeptide
• UniProt Protein Name: Receptor-type tyrosine-protein phosphatase epsilon
• UniProt Gene Name: PTPRE
• UniProt Synonym Gene Names: Protein-tyrosine phosphatase epsilon; R-PTP-epsilon
• UniProt Entry Name: PTPRE_HUMAN