IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/40.)
Rabbit anti-Human, Mouse PTPRM Polyclonal Antibody | anti-PTPRM antibody
PTPRM Antibody
Gene Names
PTPRM; RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification.
Synonyms
PTPRM, Antibody; PTPRM Antibody; RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU; anti-PTPRM antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total PTPRM protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
1.3 mg/ml (varies by lot)
Sequence Length
1465
Applicable Applications for anti-PTPRM antibody
IHC (Immunohistochemistry)
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to a region derived from internal residues of human Protein tyrosine phosphatase, receptor type, M
Target Name
PTPRM
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/40.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/40.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40.)
Related Product Information for anti-PTPRM antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Product Categories/Family for anti-PTPRM antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
165,060 Da
NCBI Official Full Name
receptor-type tyrosine-protein phosphatase mu isoform 1
NCBI Official Synonym Full Names
protein tyrosine phosphatase, receptor type, M
NCBI Official Symbol
PTPRM
NCBI Official Synonym Symbols
RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU
NCBI Protein Information
receptor-type tyrosine-protein phosphatase mu
UniProt Protein Name
Receptor-type tyrosine-protein phosphatase mu
UniProt Gene Name
PTPRM
UniProt Synonym Gene Names
PTPRL1; Protein-tyrosine phosphatase mu; R-PTP-mu
UniProt Entry Name
PTPRM_HUMAN
Similar Products
Product Notes
The PTPRM ptprm (Catalog #AAA307727) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTPRM Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PTPRM can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PTPRM ptprm for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTPRM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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