WB (Western Blot)
(PURA Antibody (C-term) western blot analysis in A549,NCI-H292 cell line lysates (35ug/lane).This demonstrates the PURA antibody detected the PURA protein (arrow).)
Rabbit PURA Polyclonal Antibody | anti-PURA antibody
PURA Antibody (C-term)
Gene Names
PURA; PUR1; MRD31; PURALPHA; PUR-ALPHA
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PURA, Antibody; PURA Antibody (C-term); Transcriptional activator protein Pur-alpha; Purine-rich single-stranded DNA-binding protein alpha; PURA; PUR1; anti-PURA antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PURA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the C-terminal region of human PURA.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.4 (varies by lot)
Sequence Positions
259-287
Sequence Length
322
Applicable Applications for anti-PURA antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(PURA Antibody (C-term) western blot analysis in A549,NCI-H292 cell line lysates (35ug/lane).This demonstrates the PURA antibody detected the PURA protein (arrow).)
WB (Western Blot)
(PURA Antibody (C-term) western blot analysis in A549,NCI-H292 cell line lysates (35ug/lane).This demonstrates the PURA antibody detected the PURA protein (arrow).)
IHC (Immunohistochemistry)
(PURA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PURA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemistry)
(PURA Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PURA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-PURA antibody
This gene product is a sequence-specific, single-stranded
DNA-binding protein. It binds preferentially to the single strand
of the purine-rich element termed PUR, which is present at origins
of replication and in gene flanking regions in a variety of
eukaryotes from yeasts through humans. Thus, it is implicated in
the control of both DNA replication and transcription. Deletion of
this gene has been associated with myelodysplastic syndrome and
acute myelogenous leukemia.
DNA-binding protein. It binds preferentially to the single strand
of the purine-rich element termed PUR, which is present at origins
of replication and in gene flanking regions in a variety of
eukaryotes from yeasts through humans. Thus, it is implicated in
the control of both DNA replication and transcription. Deletion of
this gene has been associated with myelodysplastic syndrome and
acute myelogenous leukemia.
References
Inoue, T., et al. Prostate 69(8):861-873(2009)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Kaminski, R., et al. Cancer Biol. Ther. 7(12):1926-1935(2008)
Darbinian, N., et al. J. Alzheimers Dis. 15(1):71-82(2008)
Wang, L.G., et al. Cancer Res. 68(8):2678-2688(2008)
Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
Kaminski, R., et al. Cancer Biol. Ther. 7(12):1926-1935(2008)
Darbinian, N., et al. J. Alzheimers Dis. 15(1):71-82(2008)
Wang, L.G., et al. Cancer Res. 68(8):2678-2688(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34911
NCBI Official Full Name
transcriptional activator protein Pur-alpha
NCBI Official Synonym Full Names
purine-rich element binding protein A
NCBI Official Symbol
PURA
NCBI Official Synonym Symbols
PUR1; MRD31; PURALPHA; PUR-ALPHA
NCBI Protein Information
transcriptional activator protein Pur-alpha
UniProt Protein Name
Transcriptional activator protein Pur-alpha
UniProt Gene Name
PURA
UniProt Synonym Gene Names
PUR1
UniProt Entry Name
PURA_HUMAN
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Product Notes
The PURA pura (Catalog #AAA288180) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 259-287. The PURA Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's PURA can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the PURA pura for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PURA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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