Rabbit RAB21 Polyclonal Antibody | anti-RAB21 antibody

RAB21 Antibody

Cat. Num. AAA39728

• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Western Blot, ELISA
• Purity: RAB21 Antibody is affinity chromatography purified via peptide column.
• Synonyms: RAB21, Antibody; RAB21 Antibody; RAB21; KIAA0118; Ras-related protein Rab-21; RAB21, member RAS oncogene family; anti-RAB21 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This antibody is predicted to not cross-react with other Ras-related proteins
• Purity/Purification: RAB21 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 225

• Applicable Applications for anti-RAB21 antibody: IF (Immunofluorescence), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: RAB21 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human RAB21.
• Buffer: RAB21 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: RAB21 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of RAB21 in human kidney tissue with RAB21 antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of RAB21 in mouse kidney tissue lysate with RAB21 antibody at 1 μg/mL.)

Related Product Information for anti-RAB21 antibody

RAB21 Antibody: RAB21 is a member of a subfamily of small GTP-binding protein genes of the Ras superfamily that plays an important role in intracellular vesicular targeting. In non-polarized Caco-2 cells, RAB21 showed a general endoplasmic reticulum (ER)-like localization, while in polarized cells, RAB21 localized to apical vesicles. RAB21 has been shown to associate with integrin subunits and to be important for receptor entry into cells via RAB5/RAB21 endosomes. The GTPase-activating protein p120RasGAP regulates cell motility by controlling the return of the endocytosed integrins to the plasma membrane by competing with RAB21 for binding to overlapping sites on the α-tail of endocytosed integrin.

NCBI and Uniprot Product Information

• NCBI GI #: 7661922
• NCBI GeneID: 23011
• NCBI Accession #: NP_055814
• NCBI GenBank Nucleotide #: NM_014999.2
• UniProt Accession #: Q9UL25; Q14466; Q569H3
• Molecular Weight: 24,348 Da
• NCBI Official Full Name: ras-related protein Rab-21
• NCBI Official Synonym Full Names: RAB21, member RAS oncogene family
• NCBI Official Symbol: RAB21
• NCBI Protein Information: ras-related protein Rab-21
• UniProt Protein Name: Ras-related protein Rab-21
• UniProt Gene Name: RAB21
• UniProt Synonym Gene Names: KIAA0118
• UniProt Entry Name: RAB21_HUMAN