ICC (Immunocytochemistry)
(Immunocytochemistry of RAET1E in K562 cells with RAET1E at 2.5 μg/mL.)
Rabbit anti-Human, Mouse RAET1E Polyclonal Antibody | anti-RAET1E antibody
RAET1E Antibody
Gene Names
RAET1E; RL-4; LETAL; ULBP4; N2DL-4; NKG2DL4; RAET1E2; bA350J20.7
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column.
Synonyms
RAET1E, Antibody; RAET1E Antibody; Retinoic acid early transcript 1E, NKG2D ligand 4, N2DL-4, NKG2DL42, RL-4, ULBP4, LETAL; anti-RAET1E antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
RAET1E antibody is human and mouse reactive. At least four isoforms of RAET1E are known to exist; this antibody will detect all four.
Purity/Purification
Affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
263
Applicable Applications for anti-RAET1E antibody
WB (Western Blot), ELISA
Immunogen
RAET1E antibody was raised against an 18 amino acid peptide near the center of human RAET1E.
Buffer
Supplied in PBS containing 0.02% sodium azide.
Positive Control 1
EL4 Cell Lysate
Conjugate
Unconjugated
Preparation and Storage
Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of RAET1E in K562 cells with RAET1E at 2.5 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of RAET1E in K562 cells with RAET1E at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of RAET1E in EL4 cell lysate with RAET1E antibody at 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of RAET1E in EL4 cell lysate with RAET1E antibody at 1 μg/ml.)
Related Product Information for anti-RAET1E antibody
The Retinoic acid early transcript 1E (RAET1E) belongs to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3 (1). Like the related protein RAET1G, RAET1E differs from other RAET1 proteins in that they have type I membrane-spanning sequences at their carboxy termini rather than glycosylphosphatidylinositol anchor sequences (2). RAET1E functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses (1,3).
Product Categories/Family for anti-RAET1E antibody
References
Radosavlijevic M, Cuillerier B, Wilson MJ, et al. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3. Genomics 2002; 79:114-23. Bacon L, Eagle RA, Meyer M, et al. Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D. J. Immunol. 2004; 173:1078-84. Letal, a tumor-associated NKG2D immunoreceptor ligand, induces activation and expansion of effector immune cells. Cancer Biol. Ther. 2003; 2:446-51.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 29 kDa
Observed: 29 kDa
Observed: 29 kDa
NCBI Official Full Name
NKG2D ligand 4 isoform 1
NCBI Official Synonym Full Names
retinoic acid early transcript 1E
NCBI Official Symbol
RAET1E
NCBI Official Synonym Symbols
RL-4; LETAL; ULBP4; N2DL-4; NKG2DL4; RAET1E2; bA350J20.7
NCBI Protein Information
NKG2D ligand 4
UniProt Protein Name
NKG2D ligand 4
UniProt Gene Name
RAET1E
UniProt Synonym Gene Names
LETAL; N2DL4; ULBP4; N2DL-4; NKG2DL4; RL-4
UniProt Entry Name
N2DL4_HUMAN
Similar Products
Product Notes
The RAET1E raet1e (Catalog #AAA40849) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RAET1E Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RAET1E can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the RAET1E raet1e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAET1E, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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