Rabbit RBM35A Polyclonal Antibody | anti-ESRP1 antibody

RBM35A Antibody

Cat. Num. AAA39831

• Gene Names: ESRP1; RBM35A; RMB35A
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: RBM35A Antibody is affinity chromatography purified via peptide column.
• Synonyms: RBM35A, Antibody; RBM35A Antibody; RBM35A; RMB35A; Epithelial splicing regulatory protein 1; RNA-binding motif protein 35A; epithelial splicing regulatory protein 1; anti-ESRP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: RBM35A antibody is predicted to not cross-react with other RBM35/ESRP family members. At least five isoforms of RBM35A are known to exist; this antibody will detect all five.
• Purity/Purification: RBM35A Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 681

• Applicable Applications for anti-ESRP1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: RBM35A antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human RBM35A.
• Buffer: RBM35A Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: RBM35A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of RBM35A in human colon tissue cells with RBM35A antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of RBM35A in human colon tissue with RBM35A antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of RBM35A in rat colon tissue lysate with RBM35A antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-ESRP1 antibody

RBM35A Antibody: RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.

NCBI and Uniprot Product Information

• NCBI GI #: 56790297
• NCBI GeneID: 54845
• NCBI Accession #: NP_001030087
• NCBI GenBank Nucleotide #: NM_017697.3
• UniProt Accession #: Q6NXG1; Q2M2B0; Q499G3; Q6PJ86; Q9NXL8; A6NHA8; A8MPX1; E9PB47
• Molecular Weight: 73,133 Da
• NCBI Official Full Name: epithelial splicing regulatory protein 1 isoform 1
• NCBI Official Synonym Full Names: epithelial splicing regulatory protein 1
• NCBI Official Symbol: ESRP1
• NCBI Official Synonym Symbols: RBM35A; RMB35A
• NCBI Protein Information: epithelial splicing regulatory protein 1; RNA-binding protein 35A; RNA binding motif protein 35A; RNA-binding motif protein 35A
• UniProt Protein Name: Epithelial splicing regulatory protein 1
• UniProt Gene Name: ESRP1
• UniProt Synonym Gene Names: RBM35A
• UniProt Entry Name: ESRP1_HUMAN