Rabbit anti-Human, Mouse RBM35B Polyclonal Antibody | anti-ESRP2 antibody

RBM35B Antibody

Cat. Num. AAA39210

• Gene Names: ESRP2; RBM35B
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: RBM35B Antibody is affinity chromatography purified via peptide column.
• Synonyms: RBM35B, Antibody; RBM35B Antibody; RBM35B; PP7059; Epithelial splicing regulatory protein 2; RNA-binding motif protein 35B; epithelial splicing regulatory protein 2; anti-ESRP2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least three isoforms of RBM35B are known to exist; this antibody will detect all three.
• Purity/Purification: RBM35B Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 717

• Applicable Applications for anti-ESRP2 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: RBM35B antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human RBM35B.
• Buffer: RBM35B Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: RBM35B antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of RBM35B in human lung tissue cells with RBM35B antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of RBM35B in human lung tissue with RBM35B antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of RBM35B in human lung tissue lysate with RBM35B antibody at 1 μg/mL.)

Related Product Information for anti-ESRP2 antibody

RBM35B Antibody: RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.

NCBI and Uniprot Product Information

• NCBI GI #: 45935393
• NCBI GeneID: 80004
• NCBI Accession #: NP_079215
• NCBI GenBank Nucleotide #: NM_024939.2
• UniProt Accession #: Q9H6T0; Q8N6H8; Q8WZ15; Q9H6I4
• Molecular Weight: 77,364 Da
• NCBI Official Full Name: epithelial splicing regulatory protein 2
• NCBI Official Synonym Full Names: epithelial splicing regulatory protein 2
• NCBI Official Symbol: ESRP2
• NCBI Official Synonym Symbols: RBM35B
• NCBI Protein Information: epithelial splicing regulatory protein 2; RNA-binding protein 35B; RNA binding motif protein 35A; RNA binding motif protein 35B; RNA-binding motif protein 35B
• UniProt Protein Name: Epithelial splicing regulatory protein 2
• UniProt Gene Name: ESRP2
• UniProt Synonym Gene Names: RBM35B
• UniProt Entry Name: ESRP2_HUMAN