IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human heart tissue using AAA233075 at dilution of 1:100)
Rabbit anti-Human, Mouse RBM4 Polyclonal Antibody | anti-RBM4 antibody
RBM4 Antibody
Gene Names
RBM4; LARK; RBM4A; ZCRB3A; ZCCHC21
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
>95%, Protein G purified
Synonyms
RBM4, Antibody; RBM4 Antibody; RNA-binding protein 4; Lark homolog; hLark; RNA-binding motif protein 4; RNA-binding motif protein 4a; RBM4; RBM4A; anti-RBM4 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
143
Applicable Applications for anti-RBM4 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant human RNA-binding protein 4 protein (121-205AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Conjugation
Non-conjugated
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-98346
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human heart tissue using AAA233075 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human heart tissue using AAA233075 at dilution of 1:100)
WB (Western Blot)
(Western BlotPositive WB detected in:Mouse brain tissueAll lanes: RBM4 antibody at 2.8ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 41,21,17,20 kDaObserved band size: 41 kDa)
WB (Western Blot)
(Western BlotPositive WB detected in:Mouse brain tissueAll lanes: RBM4 antibody at 2.8ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 41,21,17,20 kDaObserved band size: 41 kDa)
Related Product Information for anti-RBM4 antibody
RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5'-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. Binds to intronic pyrimidine-rich sequence of the TPM1 and MAPT pre-mRNAs. Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA. Exerts a suppressive activity on Cap-dependent translation via binding to CU-rich responsive elements within the 3'UTR of mRNAs, a process increased under stress conditions or during myocytes differentiation. Recruits EIF4A1 to stimulate IRES-dependent translation initiation in respons to cellular stress. Associates to internal ribosome entry segment (IRES) in target mRNA species under stress conditions. Plays a role for miRNA-guided RNA cleavage and translation suppression by promoting association of AGO2-containing miRNPs with their cognate target mRNAs. Associates with miRNAs during muscle cell differentiation. Binds preferentially to 5'-CGCGCG[GCA]-3' motif in vitro.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,788 Da
NCBI Official Full Name
RNA-binding protein 4 isoform 2
NCBI Official Synonym Full Names
RNA binding motif protein 4
NCBI Official Symbol
RBM4
NCBI Official Synonym Symbols
LARK; RBM4A; ZCRB3A; ZCCHC21
NCBI Protein Information
RNA-binding protein 4
UniProt Protein Name
RNA-binding protein 4
UniProt Gene Name
RBM4
UniProt Synonym Gene Names
RBM4A; hLark
UniProt Entry Name
RBM4_HUMAN
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Product Notes
The RBM4 rbm4 (Catalog #AAA233075) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RBM4 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RBM4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the RBM4 rbm4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RBM4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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