IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human lung tissue using AAA230467 at dilution of 1:100)
Rabbit anti-Human, Mouse RGMA Polyclonal Antibody | anti-RGMA antibody
RGMA Antibody
Gene Names
RGMA; RGM
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
>95%, Protein G purified
Synonyms
RGMA, Antibody; RGMA Antibody; Repulsive guidance molecule A; RGM domain family member A; RGMA; RGM; anti-RGMA antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Applicable Applications for anti-RGMA antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
Recombinant Human Repulsive guidance molecule A protein (153-408AA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen Species
Homo sapiens (Human)
Research Area
Neuroscience
Target Names
RGMA
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human lung tissue using AAA230467 at dilution of 1:100)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human lung tissue using AAA230467 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human heart tissue using AAA230467 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human heart tissue using AAA230467 at dilution of 1:100)
WB (Western Blot)
(All lanes: GCDH antibody at 12ug/mlLane 1: Mouse brain tissueLane 2: Hela whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 50,48,51 kDaObserved band size: 49 kDa)
WB (Western Blot)
(All lanes: GCDH antibody at 12ug/mlLane 1: Mouse brain tissueLane 2: Hela whole cell lysateSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 50,48,51 kDaObserved band size: 49 kDa)
Related Product Information for anti-RGMA antibody
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5BARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
repulsive guidance molecule A isoform 1
NCBI Official Synonym Full Names
repulsive guidance molecule family member a
NCBI Official Symbol
RGMA
NCBI Official Synonym Symbols
RGM
NCBI Protein Information
repulsive guidance molecule A
UniProt Protein Name
Repulsive guidance molecule A
UniProt Gene Name
RGMA
UniProt Synonym Gene Names
RGM
UniProt Entry Name
RGMA_HUMAN
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Product Notes
The RGMA rgma (Catalog #AAA230467) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RGMA Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RGMA can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the RGMA rgma for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RGMA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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