Rabbit anti-Human RGS21 Polyclonal Antibody | anti-RGS21 antibody

RGS21 Antibody

Cat. Num. AAA40281

• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: RGS21 Antibody is affinity chromatography purified via peptide column.
• Synonyms: RGS21, Antibody; RGS21 Antibody; RGS21; Regulator of G-protein signaling 21; regulator of G-protein signaling 21; anti-RGS21 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: RGS21 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 152

• Applicable Applications for anti-RGS21 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: RGS21 antibody was raised against a 16 amino acid synthetic peptide near the center of human RGS21.
• Buffer: RGS21 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: RGS21 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of RGS21 in HepG2 cells with RGS21 antibody at 20 μg/mL.Green: RGS21 Antibody (5209)Blue: DAPI staining)

IF (Immunofluorescence)

(Immunofluorescence of RGS21 in HepG2 cells with RGS21 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of RGS21 in HepG2 cells with RGS21 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of RGS21 in HepG2 cell lysate with RGS21 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-RGS21 antibody

RGS21 Antibody: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.

NCBI and Uniprot Product Information

• NCBI GI #: 85540441
• NCBI GeneID: 431704
• NCBI Accession #: NP_001034241
• NCBI GenBank Nucleotide #: NM_001039152.3
• UniProt Accession #: Q2M5E4
• Molecular Weight: 17,671 Da
• NCBI Official Full Name: regulator of G-protein signaling 21
• NCBI Official Synonym Full Names: regulator of G-protein signaling 21
• NCBI Official Symbol: RGS21
• NCBI Protein Information: regulator of G-protein signaling 21; regulator of G-protein signalling 21
• UniProt Protein Name: Regulator of G-protein signaling 21
• UniProt Gene Name: RGS21
• UniProt Synonym Gene Names: RGS21
• UniProt Entry Name: RGS21_HUMAN